Reconstruction of Defect after Treatment of Bisphosphonate-related Osteonecrois of the Jaw with Staged Iliac Bone Graft

Abstract

Bisphosphonate is used widely for osteoporosis treatment, but a rising concern is the risk of osteonecrosis after long-termbisphosphonate use. Such cases are increasing, suggesting a need for research to prevent and treat bisphosphonate-relatedosteonecrosis of jaws. A 63-year-old female took bisphosphonate (Fosamax®) for four years for treatment of osteoporosisand stopped medication two months ago because of unhealed wound. She was treated with marginal mandibulectomy maintainingthe inferior border, and a metal plate was placed to prevent mandible fracture. Four months after the mandibulectomy, mandiblereconstruction surgery using iliac bone and allograft was done. Six months after reconstruction, implant placement and treatmentwith an overdenture was done without complications. This study presents a case with a successful result.