Effectiveness of Autogenous Tooth Bone Graft Combined with Growth Factor: Prospective Cohort Study

Abstract

Purpose: Autogenous tooth bone graft is proven to be efficient. We evaluated the bone healing effect and clinicalcapabilities of autogenous tooth bone materials as a scaffold when growth factor is used together with this material. Materials and Methods: Subjects were those who needed implant placement and bone graft because of missingtooth or alveolar bone defect and who kept their autogenous tooth or needed extraction of other tooth. Group Iincluded autogenous tooth bone graft with growth factor, whereas Group II had only autogenous tooth bone graft. We investigated the bone healing state through computed tomography taken just before surgery and 3 to 4 monthsafter surgery to evaluate the effectiveness of bone graft. Group I had 9 patients, whereas Group II had 5 patients. Wecompared the pre- and post-operative increase of the Hounsfield unit and bone height by analyzing the computedtomography images. Result: Sinus bone grafts numbered 8 cases, and vertical ridge augmentation was performed together with 3 casesof these. Vertical ridge augmentation was performed in 2 cases, and horizontal ridge augmentation in 1 case alone. Socket graft was done in 3 cases. The post-operative mean value of the Hounsfield unit was 960 in Group I and 836.7in Group II, but the increase was almost similar, i.e., 636.9 in Group I and 634.7 in Group II on the average. Increase ofbone height was 7.6 mm in Group I and 11.1 mm in Group II on the average. This difference was attributable to thefact that most of the cases were sinus bone graft in Group II. Conclusion: In this study, we suggest the possibility of autogenous tooth bone graft materials as a scaffold besidestheir bone healing ability.