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Inhibitory Activities of Rubi Fructus on Digestive Enzymes
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Jung Sung | - |
dc.contributor.author | Jeon, Woo Jin | - |
dc.contributor.author | You, Hyun Ju | - |
dc.contributor.author | Park, Myung Soo | - |
dc.contributor.author | Ji, Geun Eog | - |
dc.date.accessioned | 2024-05-01T01:37:09Z | - |
dc.date.available | 2024-05-01T01:37:09Z | - |
dc.date.created | 2021-12-10 | - |
dc.date.issued | 2010-10 | - |
dc.identifier.citation | Food Science and Biotechnology, Vol.19 No.5, pp.1165-1170 | - |
dc.identifier.issn | 1226-7708 | - |
dc.identifier.uri | https://hdl.handle.net/10371/200212 | - |
dc.description.abstract | Control of postprandial glucose level is important in the management of diabetes. Thus, carbohydrate-hydrolyzing enzymes have been the targets to delay absorption of glucose. In this study, water extracts of Rubi Fructus (WERF) showed inhibition on both alpha-glucosidase from baker's yeast and alpha-amylase from porcine pancreas. The IC50 value of WERF on alpha-amylase was 59.4 mu g/mL. The inhibitory activities of WERF were considerably decreased during incubation at 25, 37, and 45 degrees C for 24 hr. For the assessment of the active components tannin fraction was separated from WERF using Sephadex LH-20. Whereas LH-unbound fraction showed minimal inhibition on alpha-amylase LH-bound fraction containing enriched tannins showed higher inhibition (IC50 8.9 mu g/mL) than WERF (IC50 59.41 mu g/mL). These results suggested that tannin enriched fraction of WERF contributed to the inhibitory activity of WERF on alpha-amylase. | - |
dc.language | 영어 | - |
dc.publisher | 한국식품과학회 | - |
dc.title | Inhibitory Activities of Rubi Fructus on Digestive Enzymes | - |
dc.type | Article | - |
dc.identifier.doi | 10.1007/s10068-010-0166-z | - |
dc.citation.journaltitle | Food Science and Biotechnology | - |
dc.identifier.wosid | 000283904600005 | - |
dc.identifier.scopusid | 2-s2.0-79957665532 | - |
dc.citation.endpage | 1170 | - |
dc.citation.number | 5 | - |
dc.citation.startpage | 1165 | - |
dc.citation.volume | 19 | - |
dc.identifier.kciid | ART001491254 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | You, Hyun Ju | - |
dc.contributor.affiliatedAuthor | Ji, Geun Eog | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | WINE PROCESSING WASTE | - |
dc.subject.keywordPlus | ALPHA-GLUCOSIDASE | - |
dc.subject.keywordPlus | COREANUS MIQ. | - |
dc.subject.keywordPlus | DIABETES-MELLITUS | - |
dc.subject.keywordPlus | PINE BARK | - |
dc.subject.keywordPlus | AMYLASE | - |
dc.subject.keywordPlus | EXTRACT | - |
dc.subject.keywordPlus | RATS | - |
dc.subject.keywordPlus | NIGA-ICHIGOSIDE-F-1 | - |
dc.subject.keywordPlus | ELLAGITANNINS | - |
dc.subject.keywordAuthor | Rubi Fructus | - |
dc.subject.keywordAuthor | alpha-glucosidase inhibitor | - |
dc.subject.keywordAuthor | alpha-amylase inhibitor | - |
dc.subject.keywordAuthor | tannin | - |
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