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Analysis of osteogenic potential on 3mol% yttria-stabilized tetragonal zirconia polycrystals and two different niobium oxide containing zirconia ceramics
DC Field | Value | Language |
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dc.contributor.author | Aung Thu Hein | - |
dc.contributor.author | Cho, Young-Dan | - |
dc.contributor.author | Jo, Ye-Hyeon | - |
dc.contributor.author | Kim, Dae-Joon | - |
dc.contributor.author | Han, Jung-Suk | - |
dc.date.accessioned | 2024-05-02T06:03:10Z | - |
dc.date.available | 2024-05-02T06:03:10Z | - |
dc.date.created | 2019-07-02 | - |
dc.date.created | 2019-07-02 | - |
dc.date.created | 2019-07-02 | - |
dc.date.issued | 2018-04 | - |
dc.identifier.citation | The Journal of Advanced of Prosthodontics, Vol.10 No.2, pp.147-154 | - |
dc.identifier.issn | 2005-7806 | - |
dc.identifier.uri | https://hdl.handle.net/10371/200574 | - |
dc.description.abstract | PURPOSE. This study was performed to evaluate the osteogenic potential of 3mol% yttria-stabilized tetragonal zirconia polycrystals (3Y-TZP) and niobium oxide containing Y-TZPs with specific ratios, new (Y,Nb)-TZPs, namely YN4533 and YN4533/Al20 discs. MATERIALS AND METHODS. 3Y-TZP, YN4533 and YN4533/Al20 discs (15 mm diameter and 1 mm thickness) were prepared and their average surface roughness (R-a) and surface topography were analyzed using 3-D confocal laser microscope (CLSM) and scanning electron microscope (SEM). Mouse pre-osteoblast MC3T3-E1 cells were seeded onto all zirconia discs and evaluated with regard to cell attachment and morphology by (CLSM), cell proliferation by PicoGreen assay, and cell differentiation by Reverse-Transcription PCR and Quantitative Real-Time PCR, and alkaline phosphatase (Alp) staining. RESULTS. The cellular morphology of MC3T3-E1 pre-osteoblasts was more stretched on a smooth surface than on a rough surface, regardless of the material. Cellular proliferation was higher on smooth surfaces, but there were no significant differences between 3Y-TZP, YN4533, and YN4533/Al20. Osteoblast differentiation patterns on YN4533 and YN4533/Al20 were similar to or slightly higher than seen in 3Y-TZP. Although there were no significant differences in bone marker gene expression (alkaline phosphatase and osteocalcin), Alp staining indicated better osteoblast differentiation on YN4533 and YN4533/Al20 compared to 3Y-TZP. CONCLUSION. Based on these results, niobium oxide containing Y-TZPs have comparable osteogenic potential to 3Y-TZP and are expected to be suitable alternative ceramics dental implant materials to titanium for aesthetically important areas. | - |
dc.language | 영어 | - |
dc.publisher | 대한치과보철학회 | - |
dc.title | Analysis of osteogenic potential on 3mol% yttria-stabilized tetragonal zirconia polycrystals and two different niobium oxide containing zirconia ceramics | - |
dc.type | Article | - |
dc.identifier.doi | 10.4047/jap.2018.10.2.147 | - |
dc.citation.journaltitle | The Journal of Advanced of Prosthodontics | - |
dc.identifier.wosid | 000431063600010 | - |
dc.identifier.scopusid | 2-s2.0-85045907544 | - |
dc.citation.endpage | 154 | - |
dc.citation.number | 2 | - |
dc.citation.startpage | 147 | - |
dc.citation.volume | 10 | - |
dc.identifier.kciid | ART002337939 | - |
dc.description.isOpenAccess | Y | - |
dc.contributor.affiliatedAuthor | Cho, Young-Dan | - |
dc.contributor.affiliatedAuthor | Han, Jung-Suk | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | DIFFERENT SURFACE TOPOGRAPHIES | - |
dc.subject.keywordPlus | TITANIUM IMPLANTS | - |
dc.subject.keywordPlus | DENTAL IMPLANTS | - |
dc.subject.keywordPlus | FRACTURE STRENGTH | - |
dc.subject.keywordPlus | PHASE-STABILITY | - |
dc.subject.keywordPlus | METAL | - |
dc.subject.keywordPlus | OSSEOINTEGRATION | - |
dc.subject.keywordPlus | CELLS | - |
dc.subject.keywordPlus | BONE | - |
dc.subject.keywordPlus | BIOCOMPATIBILITY | - |
dc.subject.keywordAuthor | Dental implant | - |
dc.subject.keywordAuthor | Niobium | - |
dc.subject.keywordAuthor | Zirconia | - |
dc.subject.keywordAuthor | Low temperature degradation (LTD) | - |
dc.subject.keywordAuthor | Osteogenic potential | - |
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