Publications
Detailed Information
One-year adherence to clinic visits after highly active antiretroviral therapy: a predictor of clinical progress in HIV patients
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Park, W B | - |
dc.contributor.author | Choe, P G | - |
dc.contributor.author | Kim, S-H | - |
dc.contributor.author | Jo, J H | - |
dc.contributor.author | Bang, J H | - |
dc.contributor.author | Kim, H B | - |
dc.contributor.author | Kim, N J | - |
dc.contributor.author | Oh, M | - |
dc.contributor.author | Choe, K W | - |
dc.date.accessioned | 2009-12-31T08:30:56Z | - |
dc.date.available | 2009-12-31T08:30:56Z | - |
dc.date.issued | 2007-02-20 | - |
dc.identifier.citation | J Intern Med. 2007 Mar;261(3):268-75. | en |
dc.identifier.issn | 0954-6820 (Print) | - |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17305649 | - |
dc.identifier.uri | https://hdl.handle.net/10371/24765 | - |
dc.description.abstract | OBJECTIVE: To determine whether adherence to clinic visits early after initiation of highly active antiretroviral therapy (HAART) is predictive of long-term clinical outcome. DESIGN: Observational cohort study. SETTING: A tertiary referral hospital. SUBJECTS: A total of 387 adult HIV patients who were followed for at least 1 year after initiation of HAART between January 1998 and December 2004. MAIN OUTCOME MEASUREMENTS: The effect of 1-year adherence to clinic visits on the occurrence of new AIDS-defining illness or death was assessed using Kaplan-Meier survival estimates, and hazard ratios were estimated using Cox proportional hazards regression model. RESULTS: Multivariate analysis revealed that advanced clinical stage, fewer new drugs in HAART, and longer total elapsed time without clinical visits for 1 year after HAART were all significant risk factors for the occurrence of new AIDS-defining illnesses or death. Compared with no missed visits, the hazard ratio adjusted by clinical stage and number of new drugs in HAART was 2.87 (95% confidence interval [CI], 1.34-6.16, P = 0.007) for one missed appointment, 4.37 (95% CI: 1.74-10.98, P = 0.002) for two, and 8.19 (95% CI: 2.95-22.78, P < 0.001) for three or more. CONCLUSION: Adherence to clinic visits early after initiation of HAART is an independent predictor for long-term clinical progression in HIV patients. | en |
dc.language.iso | en | - |
dc.publisher | Wiley-Blackwell | en |
dc.subject | Adult | en |
dc.subject | Ambulatory Care/psychology/*statistics & numerical data | en |
dc.subject | Anti-HIV Agents/*therapeutic use | en |
dc.subject | Cohort Studies | en |
dc.subject | Female | en |
dc.subject | HIV Infections/*drug therapy/psychology | en |
dc.subject | Humans | en |
dc.subject | Male | en |
dc.subject | Middle Aged | en |
dc.subject | Patient Compliance/*statistics & numerical data | en |
dc.subject | Regression Analysis | en |
dc.subject | Risk Factors | en |
dc.subject | Treatment Outcome | en |
dc.subject | Antiretroviral Therapy, Highly Active | - |
dc.title | One-year adherence to clinic visits after highly active antiretroviral therapy: a predictor of clinical progress in HIV patients | en |
dc.type | Article | en |
dc.identifier.doi | 10.1111/j.1365-2796.2006.01762.x | - |
- Appears in Collections:
- Files in This Item:
- There are no files associated with this item.
Item View & Download Count
Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.