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Hematuria and proteinuria in a mass school urine screening test

Cited 49 time in Web of Science Cited 61 time in Scopus
Authors
Park, Yong-Hoon; Choi, Jung-Youn; Chung, Hyo-Seok; Koo, Ja-Wook; Kim, Su-Yung; Namgoong, Mee-Kyung; Park, Young-Seo; Yoo, Kee-Hwan; Lee, Kyung-Yil; Lee, Dae-Yeol; Lee, Seung-Joo; Lee, Ji-Eun; Chung, Woo-Yeong; Hah, Tae-Sun; Cheong, Hae-Il; Choi, Yong; Lee, Kyung-Soo
Issue Date
2005-06-11
Publisher
Springer Verlag
Citation
Pediatr Nephrol. 2005 Aug;20(8):1126-30. Epub 2005 Jun 10.
Keywords
AdolescentChildFemaleHematuria/*epidemiology/pathologyHumansKidney Glomerulus/pathologyKorea/epidemiologyMale*Mass ScreeningProteinuria/*epidemiology/pathology
Abstract
A total of 1,044 school children identified with hematuria and/or proteinuria during a mass school urine screening test were referred to pediatric nephrologists at 13 hospitals in Korea. These children had isolated hematuria (IH) (60.1%), isolated proteinuria (IP) (26.4%: transient, 19.6%; orthostatic, 4.9%; persistent, 1.9%) or combined hematuria and proteinuria (CHP) (13.5%). The patient's history, physical examination, laboratory tests, kidney ultrasound and Doppler ultrasonography were obtained. Renal biopsies were performed on 113 children who showed severe proteinuria, hypertension, abnormal renal function, family history of chronic renal disease, systemic diseases or persistent hematuria and/or proteinuria for more than 12 months. IgA nephropathy (IgAN), thin basement membrane nephropathy (TBMN), membranoproliferative glomerulonephritis (MPGN), focal segmental glomerulosclerosis (FSGS), other GN, Alport syndrome and lupus nephritis were detected. IgAN and TBMN were the most common causes in the CHP group and IH group, respectively. Abnormal findings on the renal ultrasound with or without Doppler ultrasonography were noted in 147 cases (suspected nutcracker phenomenon, 65; increased parenchymal echogenicity, 40; hydronephrosis, 15). This study showed that the use of a mass school urine screening program can detect chronic renal disease in its early stage and recommends that more attention should be paid to identifying those children with CHP and massive proteinuria. A school urine screening program can detect chronic renal disease in its early stage. When mass screening is used, the initial aggressive diagnostic procedures such as renal biopsy are not needed. In addition, a regular follow-up for those children with IH and IP is certainly warranted.
ISSN
0931-041X (Print)
Language
English
URI
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15947990

http://hdl.handle.net/10371/26680
DOI
https://doi.org/10.1007/s00467-005-1915-8
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Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Pediatrics (소아과학전공)Journal Papers (저널논문_소아과학전공)
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