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The prevalence of and risk factors for erosive oesophagitis and non-erosive reflux disease: a nationwide multicentre prospective study in Korea
DC Field | Value | Language |
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dc.contributor.author | Kim, N | - |
dc.contributor.author | Lee, S W | - |
dc.contributor.author | Cho, S I | - |
dc.contributor.author | Park, C G | - |
dc.contributor.author | Yang, C H | - |
dc.contributor.author | Kim, H S | - |
dc.contributor.author | Rew, J S | - |
dc.contributor.author | Moon, J S | - |
dc.contributor.author | Kim, S | - |
dc.contributor.author | Park, S H | - |
dc.contributor.author | Jung, H C | - |
dc.contributor.author | Chung, I S | - |
dc.date.accessioned | 2010-01-07T04:52:57Z | - |
dc.date.available | 2010-01-07T04:52:57Z | - |
dc.date.issued | 2007-11-02 | - |
dc.identifier.citation | Aliment Pharmacol Ther. 2008 Jan 15;27(2):173-85. Epub 2007 Oct 25. | en |
dc.identifier.issn | 1365-2036 (Electronic) | - |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17973646 | - |
dc.identifier.uri | https://hdl.handle.net/10371/28167 | - |
dc.description.abstract | BACKGROUND: Prospective nationwide multicentre studies that have evaluated endoscopic findings and reflux symptoms using a well-designed questionnaire are very rare. AIM: To compare the prevalence rates of and risk factors for erosive oesophagitis and non-erosive reflux disease (NERD) in the Korean population. METHODS: A gastroscopic examination was performed on 25 536 subjects who visited 40 Healthcare Centers for a health check-up. A gastro-oesophageal reflux questionnaire and multivariate analysis were used to determine the risk factors for erosive oesophagitis and NERD. RESULTS: 2019 (8%) and 996 subjects (4%) had erosive oesophagitis and non-erosive reflux disease, respectively; only 58% of subjects with erosive oesophagitis had reflux symptoms. Multivariate analysis showed that the risk factors for erosive oesophagitis and NERD differed, i.e. those of erosive oesophagitis were male, a Helicobacter pylori eradication history, alcohol, body mass index > or =25 and hiatal hernia. In contrast, the risk factors for NERD were female, age <40 and > or =60 vs. 40-59 years, body mass index <23 and a monthly income <$1000, glucose > or =126 mg/dL, smoking, a stooping posture at work and antibiotic usage. CONCLUSIONS: The prevalence rates of erosive oesophagitis and NERD were 8% and 4%, respectively, in Korean health check-up subjects. The risk factors for erosive oesophagitis and NERD were found to differ, which indicates that their underlying pathogeneses are distinct. | en |
dc.language.iso | en | en |
dc.publisher | Wiley-Blackwell | en |
dc.subject | Adolescent | en |
dc.subject | Adult | en |
dc.subject | Aged | en |
dc.subject | Alcoholic Beverages/adverse effects | en |
dc.subject | Blood Glucose/metabolism | en |
dc.subject | Body Mass Index | en |
dc.subject | Epidemiologic Factors | en |
dc.subject | Esophagitis/*epidemiology/etiology/physiopathology | en |
dc.subject | Female | en |
dc.subject | Gastroesophageal Reflux/*epidemiology | en |
dc.subject | Gastroscopy | en |
dc.subject | Humans | en |
dc.subject | Korea/epidemiology | en |
dc.subject | Male | en |
dc.subject | Middle Aged | en |
dc.subject | Posture | en |
dc.subject | Prevalence | en |
dc.subject | Prospective Studies | en |
dc.subject | Smoking/adverse effects | en |
dc.title | The prevalence of and risk factors for erosive oesophagitis and non-erosive reflux disease: a nationwide multicentre prospective study in Korea | en |
dc.type | Article | en |
dc.identifier.doi | 10.1111/j.1365-2036.2007.03561.x | - |
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