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Risk factor analysis for development of asymptomatic carotid stenosis in Koreans

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Authors
Lim, Yun Jeong; Kim, Young-Wook; Choe, Yeon Kyan; Ki, Chang-Seok; Park, Sue Kyung
Issue Date
2006-02-16
Publisher
Korean Academy of Medical Science
Citation
J Korean Med Sci. 2006 Feb;21(1):15-9.
Keywords
AdultAge FactorsAgedCarotid Stenosis/blood/*epidemiology/etiologyCholesterol/bloodCholesterol, LDL/bloodFemaleHumansKorea/epidemiologyLogistic ModelsMaleMiddle AgedMultivariate AnalysisPrevalenceRetrospective StudiesRisk FactorsSmoking/adverse effects
Abstract
Many risk factors for atherosclerosis have been proposed to identify high risk individuals. We conducted a retrospective study to determine the risk factors for development of carotid stenosis (CS) in Koreans. Database of 2,805 subjects who underwent a check up of carotid artery for health examination were analyzed. Stenosis (%) of common carotid artery or proximal internal carotid artery was examined with ultrasonography. Subjects were divided into 2 groups (Group I; CS <10%, Group II; CS >or= 30%). We compared demographic, laboratory and clinical data between 2 groups to determine the risk factors of CS. One hundred ninety seven subjects (7.0%) were categorized as Group II. At age- and sex-adjusted multivariate analysis, diabetes mellitus, hypertension, cerebrovascular disease, ischemic heart disease, hyperlipidemia, aspirin medication, current smoking, fasting glucose, total cholesterol, low density lipoprotein-cholesterol (LDL-C) and leukocyte count were significant risk factors of CS. At stepwise logistic regression analysis, age, hypertension, hyperlipidemia, LDL-C and leukocyte count were independent risk factors. At subgroup analysis by smoking, age and leukocyte count were independent risk factors in smoker and age and hypertension in nonsmoker.
ISSN
1011-8934 (Print)
Language
English
URI
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16479058

http://hdl.handle.net/10371/29272
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College of Medicine/School of Medicine (의과대학/대학원)Preventive Medicine (예방의학전공)Journal Papers (저널논문_예방의학전공)
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