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Cervical length and the risk of microbial invasion of the amniotic cavity in women with preterm premature rupture of membranes

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dc.contributor.authorHong, Joon Seok-
dc.contributor.authorPark, Kyo Hoon-
dc.contributor.authorNoh, Jae Hong-
dc.contributor.authorSuh, Young Hoon-
dc.date.accessioned2010-01-11T07:11:55Z-
dc.date.available2010-01-11T07:11:55Z-
dc.date.issued2007-08-31-
dc.identifier.citationJ Korean Med Sci. 2007 Aug;22(4):713-7.en
dc.identifier.issn1011-8934 (Print)-
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17728515-
dc.identifier.urihttp://hdl.handle.net/10371/29367-
dc.description.abstractThe aims of this study were to determine whether sonographically measured cervical length is of value in the identification of microbial invasion of the amniotic cavity in women with preterm premature rupture of membranes (PPROM) and to compare its performance with maternal blood C-reactive protein (CRP), white blood cell count (WBC), and amniotic fluid (AF) WBC. This prospective observational study enrolled 50 singleton pregnancies with PPROM. Transvaginal ultrasound for measurement of cervical length was performed and maternal blood was collected for the determination of CRP and WBC at the time of amniocentesis. AF obtained by amniocentesis was cultured and WBC determined. The prevalence of a positive amniotic fluid culture was 26% (13/50). Patients with positive amniotic fluid cultures had a significantly shorter median cervical length and higher median CRP, WBC, and AF WBC than did those with negative cultures. Multiple logistic regression indicated that only cervical length had a significant relationship with the log odds of a positive AF culture. Transvaginal sonographic measurement of cervical length is valuable in the identification of microbial invasion of amniotic cavity in women with PPROM. Cervical length performs better than AF WBC, maternal blood CRP, and WBC in the identification of a positive amniotic fluid culture.en
dc.language.isoenen
dc.publisherKorean Academy of Medical Scienceen
dc.subjectAdulten
dc.subjectAmniocentesis/methodsen
dc.subjectAmniotic Fluid/*microbiologyen
dc.subjectBacterial Infections/*complicationsen
dc.subjectC-Reactive Protein/metabolismen
dc.subjectCervix Uteri/*ultrasonographyen
dc.subjectFemaleen
dc.subjectFetal Membranes, Premature Rupture/etiology/*ultrasonographyen
dc.subjectGestational Ageen
dc.subjectHumansen
dc.subjectLeukocyte Counten
dc.subjectLogistic Modelsen
dc.subjectMaternal Ageen
dc.subjectPregnancyen
dc.subjectPregnancy Complications, Infectious/blood/etiology/ultrasonographyen
dc.subjectProspective Studiesen
dc.subjectRisk Factorsen
dc.subjectUltrasonography/methodsen
dc.titleCervical length and the risk of microbial invasion of the amniotic cavity in women with preterm premature rupture of membranesen
dc.typeArticleen
dc.contributor.AlternativeAuthor홍준석-
dc.contributor.AlternativeAuthor박교훈-
dc.contributor.AlternativeAuthor노재홍-
dc.contributor.AlternativeAuthor서영훈-
Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Obstetrics & Gynecology (산부인과전공)Journal Papers (저널논문_산부인과학전공)
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