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Neuropsychological profiles of patients with obsessive-compulsive disorder: early onset versus late onset
Cited 30 time in
Web of Science
Cited 27 time in Scopus
- Authors
- Issue Date
- 2006-12-15
- Publisher
- Cambridge University Press
- Citation
- J Int Neuropsychol Soc. 2007 Jan;13(1):30-7.
- Keywords
- Adult ; Age Factors ; Age of Onset ; Cognition Disorders/diagnosis/*epidemiology ; Female ; Humans ; Male ; Neuropsychological Tests ; Obsessive-Compulsive Disorder/diagnosis/*epidemiology/psychology ; Severity of Illness Index
- Abstract
- In this study, we assess the neuropsychological profiles of both early and late symptom-onset obsessive-compulsive disorder (OCD) patients. The early and late-onset OCD patients are compared to the control group with a series of neuropsychological measurements. The late-onset OCD patients exhibited impaired performance on the immediate and the delayed recall conditions of the Rey-Osterrieth Complex Figure Test (RCFT) and the letter and category fluency of the Controlled Oral Word Association Test (COWA), compared to the normal controls and the early-onset OCD patients. The controls and early-onset OCD patients did not differ on any of the neuropsychological measurements taken in this study. These results suggest that different neurophysiological mechanisms are in play in early and late-onset OCD patients, and age of onset can serve as a potential marker for the subtyping of OCD.
- ISSN
- 1355-6177 (Print)
- Language
- English
- URI
- http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=595688
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17166301
https://hdl.handle.net/10371/29546
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