S-Space College of Medicine/School of Medicine (의과대학/대학원) Psychiatry (정신과학전공) Journal Papers (저널논문_정신과학전공)
Neuropsychological profiles of patients with obsessive-compulsive disorder: early onset versus late onset
- Hwang, Seon Hee; Kwon, Jun Soo; Shin, Yong-Wook; Lee, Kyung Jin; Kim, Young Youn; Kim, Myung-Sun
- Issue Date
- Cambridge University Press
- J Int Neuropsychol Soc. 2007 Jan;13(1):30-7.
- Adult; Age Factors; Age of Onset; Cognition Disorders/diagnosis/*epidemiology; Female; Humans; Male; Neuropsychological Tests; Obsessive-Compulsive Disorder/diagnosis/*epidemiology/psychology; Severity of Illness Index
- In this study, we assess the neuropsychological profiles of both early and late symptom-onset obsessive-compulsive disorder (OCD) patients. The early and late-onset OCD patients are compared to the control group with a series of neuropsychological measurements. The late-onset OCD patients exhibited impaired performance on the immediate and the delayed recall conditions of the Rey-Osterrieth Complex Figure Test (RCFT) and the letter and category fluency of the Controlled Oral Word Association Test (COWA), compared to the normal controls and the early-onset OCD patients. The controls and early-onset OCD patients did not differ on any of the neuropsychological measurements taken in this study. These results suggest that different neurophysiological mechanisms are in play in early and late-onset OCD patients, and age of onset can serve as a potential marker for the subtyping of OCD.
- 1355-6177 (Print)