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Showing results 1 to 15 of 15

Issue DateTitle / Author(s) / CitationFileAltmetrics
2016-10
Secreted tryptophanyl-tRNA synthetase as a primary defence system against infection
DOI
2017-06
IL-21-mediated reversal of NK cell exhaustion facilitates anti-tumour immunity in MHC class I-deficient tumours
DOI
2018-03
Comprehensive PBPK model of rifampicin for quantitative prediction of complex drug-drug interactions: CYP3A/2C9 induction and OATP inhibition effects

Asaumi, Ryuta; Toshimoto, Kota; Tobe, Yoshifusa; Hashizume, Kenta; Ken-ichi Nunoya; Imawaka, Haruo; Lee, Woo In; Sugiyama, Yuichi

CPT: Pharmacometrics and Systems Pharmacology, Vol.7 No.3, pp.186-196

DOI
2018-04
Curcumin interacts directly with the Cysteine 259 residue of STAT3 and induces apoptosis in H-Ras transformed human mammary epithelial cells
DOI
2018-07
Application of PBPK modeling and virtual clinical study approaches to predict the outcomes of CYP2D6 genotype-guided dosing of tamoxifen

Nakamura, Toshimichi; Toshimoto, Kota; Lee, Wooin; Imamura, Chiyo K.; Tanigawara, Yusuke; Sugiyama, Yuichi

CPT: Pharmacometrics and Systems Pharmacology, Vol.7 No.7, pp.474-482

DOI
2019-03
Small-molecule inhibitor of HIyU attenuates virulence of Vibrio species
DOI
2019-06
Physiologically-Based Pharmacokinetic Modeling Analysis for Quantitative Prediction of Renal Transporter-Mediated Interactions Between Metformin and Cimetidine

Nishiyama, Kotaro; Toshimoto, Kota; Lee, Wooin; Ishiguro, Naoki; Bister, Bojan; Sugiyama, Yuichi

CPT: Pharmacometrics and Systems Pharmacology, Vol.8 No.6, pp.396-406

DOI
2019-11
Expanded Physiologically-Based Pharmacokinetic Model of Rifampicin for Predicting Interactions With Drugs and an Endogenous Biomarker via Complex Mechanisms Including Organic Anion Transporting Polypeptide 1B Induction

Asaumi, Ryuta; Menzel, Karsten; Lee, Wooin; Nunoya, Ken-Ichi; Imawaka, Haruo; Kusuhara, Hiroyuki; Sugiyama, Yuichi

CPT: Pharmacometrics and Systems Pharmacology, Vol.8 No.11, pp.845-857

DOI
2020-06
Connectivity map-based drug repositioning of bortezomib to reverse the metastatic effect of GALNT14 in lung cancer
DOI
2020-11
Phase 0/microdosing approaches: time for mainstream application in drug development?

Burt, Tal; Young, Graeme; Lee, Wooin; Kusuhara, Hiroyuki; Langer, Oliver; Rowland, Malcolm; Sugiyama, Yuichi

Nature Reviews Drug Discovery, Vol.19 No.11, pp.801-818

DOI
2021-02
L1 retrotransposons exploit RNA m(6)A modification as an evolutionary driving force
DOI
2022-05
Structural anatomy of Protein Kinase C C1 domain interactions with diacylglycerol and other agonists
DOI
2022-06
A novel HSP90 inhibitor SL-145 suppresses metastatic triple-negative breast cancer without triggering the heat shock response
DOI
2022-11
Actinopolymorphols E and F, pyrazine alkaloids from a marine sediment-derived bacterium Streptomyces sp
DOI
2023-08
Tailoring renal-clearable zwitterionic cyclodextrin for colorectal cancer-selective drug delivery
DOI
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