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Transfusion for a patient of cis-AB blood type undergoing a redo cardiac operation

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Authors
Yoon, S. Z.; Lee, H. M.; Kim, H. S.; Kim, S. D.; Oh, A. Y.; Kim, C. S.
Issue Date
2005-03-08
Publisher
Oxford University Press
Citation
Br J Anaesth. 2005 Jun;94(6):733-4. Epub 2005 Mar 4.
Keywords
ABO Blood-Group System/*geneticsAdolescentBlood Grouping and CrossmatchingBlood Transfusion/*methodsGalactosyltransferases/geneticsHeart Defects, Congenital/blood/*surgeryHumansMalePoint MutationReoperationRh-Hr Blood-Group System
Abstract
cis-AB, a rare ABO genotype, is the result of a mutated gene resulting in dual specific hybrid enzymes. A single-point mutation reverses the specificity of human blood group B synthesizing galactosyltransferase. This may lead to misclassification in ABO grouping and adverse transfusion reactions. Recently, the authors experienced a case of a patient with cis-AB blood type undergoing pulmonary valve replacement and tricuspid valvuloplasty. We transfused the patient with Rh+ A packed red blood cell, fresh frozen plasma and platelet concentrates without any clinically significant transfusion reactions.
ISSN
0007-0912 (Print)
Language
English
URI
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15749736

http://hdl.handle.net/10371/36691
DOI
https://doi.org/10.1093/bja/aei101
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College of Medicine/School of Medicine (의과대학/대학원)Anesthesiology and Pain Medicine (마취통증의학전공)Journal Papers (저널논문_마취통증의학전공)
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