Publications
Detailed Information
Effects of PVA sponge containing chitooligosaccharide in the early stage of wound healing
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Min, Byung-Moo | - |
dc.contributor.author | You, Young | - |
dc.contributor.author | Park, Won-Ho | - |
dc.contributor.author | Ko, Bub-Min | - |
dc.date.accessioned | 2010-02-01T06:02:13Z | - |
dc.date.available | 2010-02-01T06:02:13Z | - |
dc.date.issued | 2004-03 | - |
dc.identifier.citation | JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE. 15 (2004) 297-301. | en |
dc.identifier.issn | 0957-4530 | - |
dc.identifier.uri | https://hdl.handle.net/10371/47240 | - |
dc.description.abstract | Poly(vinyl alcohol) (PVA) sponges with different chitooligosaccharide (COS) content were prepared for wound-dressing application. The morphological structure of PVA sponges was observed by scanning electron microscopy. As the concentration of COS-loaded PVA sponge increased, the average pore size of sponge decreased and the release rate of COS from the sponge also slightly decreased. The accelerating effect of the COS-loaded PVA sponges on open wound healing in rats was investigated by macroscopic examination and measurement of wound area. The COS-loaded sponges were found to be very effective as a wound-healing accelerator in the early stage of wound healing. The wound treated with the COS-loaded PVA sponge was almost reepithelialized, granulation tissues in the wound were considerably replaced by fibrosis at 8 days after initial wounding. The COS-loaded PVA sponge was considered to be a suitable wound-healing formulation due to its easy preparation and high effectiveness | en |
dc.language.iso | en | en |
dc.publisher | Springer Verlag | en |
dc.title | Effects of PVA sponge containing chitooligosaccharide in the early stage of wound healing | en |
dc.type | Article | en |
dc.contributor.AlternativeAuthor | 민병무 | - |
dc.contributor.AlternativeAuthor | 유영 | - |
dc.contributor.AlternativeAuthor | 박원호 | - |
dc.contributor.AlternativeAuthor | 고법민 | - |
dc.identifier.doi | 10.1023/B:JMSM.0000015491.91918.64 | - |
- Appears in Collections:
- Files in This Item:
- There are no files associated with this item.
Item View & Download Count
Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.