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생체유래 골이식재 (OSC-B)의 안전성 및 유효성에 관한 연구
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 박호남 | - |
dc.contributor.author | 한상혁 | - |
dc.contributor.author | 김경화 | - |
dc.contributor.author | 이상철 | - |
dc.contributor.author | 박윤정 | - |
dc.contributor.author | 이상훈 | - |
dc.contributor.author | 김태일 | - |
dc.contributor.author | 설양조 | - |
dc.contributor.author | 구영 | - |
dc.contributor.author | 류인철 | - |
dc.contributor.author | 한수부 | - |
dc.contributor.author | 정종평 | - |
dc.date.accessioned | 2010-02-01T06:14:14Z | - |
dc.date.available | 2010-02-01T06:14:14Z | - |
dc.date.issued | 2005 | - |
dc.identifier.citation | 대한치주과학회지 2005;35:335-343. | en |
dc.identifier.issn | 0250-3352 | - |
dc.identifier.uri | http://uci.or.kr/G100:I100-KOI(KISTI1.1003/JNL.JAKO200521452724025) | - |
dc.identifier.uri | https://hdl.handle.net/10371/47480 | - |
dc.description.abstract | Inorganic bovine bone mineral has been widely researched as bone substitution materials in orthopedic and oral and maxillofacial application. OCS-B(NIBEC, Korea) is newly-developed inorganic bovine bone mineral. The aim of this study is to evaluate the safety and efficacy of bovine bone-derived bone graft material(OCS-B). Micro-structure of newly-developed inorganic bovine bone mineral(OCS-B) was analyzed by scanning electron microscope(SEM). Round cranial defects with eight mm diameter were made and filled with OCS-B in rabbits. OCS-B was inserted into femoral quadrant muscle in mouse. In scanning electron microscope, OCS-B was equal to natural hydroxyapatite. Rabbits were sacrificed at 2 weeks and 4 weeks after surgery and mice were sacrificed at 1 week and 2 weeks after surgery. Decalcified specimens were prepared and observed by microscope. In calvarial defects, osteoid and new bone were formed in the neighborhood of OCS-B at 2 weeks after surgery. And at 4 weeks after surgery osteoid and new bone bridge formed flourishingly. No inflammatory cells were seen on the surface of OCS-B at 1 week and 2 weeks in mouse experimental group. It is concluded that newly-developed inorganic bovine bone mineral(OCS-B) is a flourishing bone-forming material and biocompatible material. | en |
dc.description.sponsorship | 본 연구는 과학재단 산하 ERC(지능형 생체 계면 공학 연구 센터)에서 연구비를 지원 받았습니다. | en |
dc.language.iso | ko | en |
dc.publisher | 대한치주과학회 | en |
dc.subject | bovine bone | en |
dc.subject | bone regeneration | en |
dc.subject | calvarial defect | en |
dc.title | 생체유래 골이식재 (OSC-B)의 안전성 및 유효성에 관한 연구 | en |
dc.type | Article | en |
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