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Regulation of K+ channels may enhance wound healing in the skin
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kang, Dawon | - |
dc.contributor.author | Choi, Tae Hyun | - |
dc.contributor.author | Han, Kihwan | - |
dc.contributor.author | Son, Daegu | - |
dc.contributor.author | Kim, Jun Hyung | - |
dc.contributor.author | Kim, Sang-Hyon | - |
dc.contributor.author | Park, Jungbin | - |
dc.date.accessioned | 2009-07-08T04:55:02Z | - |
dc.date.available | 2009-07-08T04:55:02Z | - |
dc.date.issued | 2008-08-29 | - |
dc.identifier.citation | Med Hypotheses 2008;71:927-929 | en |
dc.identifier.issn | 0306-9877 (print) | - |
dc.identifier.issn | 1532-2777 (online) | - |
dc.identifier.uri | https://hdl.handle.net/10371/5325 | - |
dc.description | Authors' final draft | - |
dc.description.abstract | In the process of promoting wound healing, epidermal growth factor (EGF) activates protein kinase C, protein tyrosine kinase and ERK MAPK (mitogen-activated protein kinase). The activation of these mediators in signal pathways can regulate the operation of K+ channels. In addition, the K+ channel is involved with cell migration and proliferation, both of which are requisite for wound healing. Recent studies, although not conducted on skin wounds, have found that the K+ channel is associated with wound healing and that wound healing can be promoted by regulating the K+ channels. Therefore, the authors hypothesize that healing of skin wounds could be promoted by regulating K+ channel distribution in skin keratinocytes or fibroblasts. We plan to conduct a study of the promotion of skin wound healing using K+ channel regulators. | en |
dc.description.sponsorship | This work was supported by the Korea Science and Engineering Foundation (KOSEF) grant funded by the Korea government (MOST) (No. R01-2007-000-20746-0). | en |
dc.language.iso | en | - |
dc.publisher | Elsevier | en |
dc.title | Regulation of K+ channels may enhance wound healing in the skin | en |
dc.type | Article | en |
dc.contributor.AlternativeAuthor | 강다원 | - |
dc.contributor.AlternativeAuthor | 최태현 | - |
dc.contributor.AlternativeAuthor | 한기환 | - |
dc.contributor.AlternativeAuthor | 손대구 | - |
dc.contributor.AlternativeAuthor | 김준형 | - |
dc.contributor.AlternativeAuthor | 김상현 | - |
dc.contributor.AlternativeAuthor | 박정빈 | - |
dc.identifier.doi | 10.1016/j.mehy.2008.05.038 | - |
dc.identifier.doi | 10.1016/j.mehy.2008.05.038 | - |
dc.citation.journaltitle | Medical hypotheses | - |
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