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Immunofluorescent Findings in Graves' Disease and Hashimoto's Disease
Graves 및 Hashimoto병에서의 면역형광소견

DC Field Value Language
dc.contributor.authorAhn, Il-Min-
dc.contributor.authorCho, Bo Youn-
dc.contributor.authorKoh, Chang-Soon-
dc.contributor.authorLee, Munho-
dc.contributor.authorPark, Seoung Hoe-
dc.contributor.authorKim, Yong Il-
dc.date.accessioned2009-07-17T04:58:05Z-
dc.date.available2009-07-17T04:58:05Z-
dc.date.issued1985-06-
dc.identifier.citationSeoul J Med 1985;26(2):149-156en
dc.identifier.issn0582-6802-
dc.identifier.urihttp://hdl.handle.net/10371/5688-
dc.description.abstractDireet immunofluorescent study with antisera against Ig G, A, M, C3 & fibrinogen
was performed on thyroid specimens from 21 cases of Graves' disease and 11 cases of
Hashimoto's thyroiditis to define immunofluorescent findings in each disorder and their functional
significance, with the following results;
1. Ninety five % of Graves' disease cases showed significant granular immunofluorescent
deposit along follicular basement menbrane and remainder showed scanty granular deposit on
interfollicular space.
2. Forty five % of Hashimoto's thyroiditis cases showed immunofluorescent deposit along
follicular basement membrane, whereas 63% showed deposition on interfollicular space.
3. Three cases histologically appreciated as Hashimoto's thyroiditis had significant deposit
along follicular basement membrane, and all of them showed physical findings and past
history compatible with Graves' disease.
4. 'there was no significant correlation between immunofluorescent deposit, and thyroid
function or the presence of thyroid autoantibodies.
5. Comparing immunofluorescent studies with light microscopic findings, degree of immunofluorescent
deposit along follicular basement membrane was correlated well with the
degree of lymphocytic infiltration in Graves' disease.
In this study, it was shown that the pattern of immunofluorescent deposition in Graves'
disease was different from that of Hashimoto's disease, and the degree of immunofluorescent
deposit along follicular basement membrane was correlated well with the degree of lymphocytic
infiltration in Graves' disease.
en
dc.language.isoenen
dc.publisherSeoul National University College of Medicineen
dc.subjectImmunofluorescent studyen
dc.subjectHashimoto's diseaseen
dc.subjectGraves' diseaseen
dc.subjectAutoimmunityen
dc.titleImmunofluorescent Findings in Graves' Disease and Hashimoto's Diseaseen
dc.title.alternativeGraves 및 Hashimoto병에서의 면역형광소견en
dc.typeSNU Journalen
dc.contributor.AlternativeAuthor안일민-
dc.contributor.AlternativeAuthor조보연-
dc.contributor.AlternativeAuthor고창순-
dc.contributor.AlternativeAuthor이문호-
dc.contributor.AlternativeAuthor박성혜-
dc.contributor.AlternativeAuthor김용일-
dc.citation.journaltitle서울 의대 잡지 = 서울 의대 학술지 = Seoul Journal of Medicine-
Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Dept. of Medicine (의학과)The Seoul Journal of MedicineThe Seoul Journal of Medicine Vol. 26 No.2 (1985)
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