저혈당증을 수반한 후복막 방추형 세포종의 1예
Retro-Peritoneal Spindle-Cell Tumor Associated with Hypoglycemia

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김자훈; 이영철; 손춘호; 한심석; 김응진; 김정룡; 이성수; 이상국; 김용일
Issue Date
Seoul National University College of Medicine
Seoul J Med 1962;3(2):81-90
A case of 48 year old Korean male with a huge
extra-pancreatic retro-peritoneal tumor associated with
marked hypoglycemia was reported.
The tumor weighed 2.200 gm., measured 20X 20X 8
em., and microscopically was composed largely of spindle-
cell masses with lowgrade malignancy accompanied by scanty epithelial or glandular components in few
areas., Few giant tumor cells were observed. However,
the epithelial or glandular tumor components did not
reveal any morphological resemblance to acinar or insular
structures of the normal pancreas. although some
acinus-like structures contained homogeneous eosinophilic
Van Giesen's stain and Reticulum stain revealed
absence of collagen fibers and reticulum fibers in the
spindle-cell masses.
After removal of the tumor, hypoglycemic reaction
disappeared; and the patient did well until after
7 months.
The oncologic entity or histologic and histogenetic
classification of this tumor was discussed along with
previously reported 20 or more cases collected in the
literature. Authors' discussion inclined towards the possi
bility of the functioning extrapancreatic islet cell tumor
masked by metaplastic spindle-cell-sarcomatous picture.
Reduction of the patient's blood pressure to normal
level was not clearly understood, but was discuss
ed along the line of Goldblatt mechanism.
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College of Medicine/School of Medicine (의과대학/대학원)Dept. of Medicine (의학과)The Seoul Journal of MedicineThe Seoul Journal of Medicine Vol. 03 No.2 (1962)
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