Publications
Detailed Information
Rapid induction of malignant tumor in Sprague-Dawley rats by injection of RME-ras cells
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Park, Joo-Cheol | - |
dc.contributor.author | Kim, Soo-A | - |
dc.contributor.author | Kim, Hyun-Woo | - |
dc.contributor.author | Kim, Do-Kyung | - |
dc.contributor.author | Kim, Su-Gwan | - |
dc.contributor.author | Kang, Dong-Wan | - |
dc.contributor.author | Kim, Si-Wouk | - |
dc.contributor.author | Ahn, Sang-Gun | - |
dc.contributor.author | Yoon, Jung-Hoon | - |
dc.date.accessioned | 2010-04-01T05:17:38Z | - |
dc.date.available | 2010-04-01T05:17:38Z | - |
dc.date.issued | 2006-04 | - |
dc.identifier.citation | CANCER LETTERS, 235 (2006), 53-59. | en |
dc.identifier.issn | 0304-3835 | - |
dc.identifier.uri | https://hdl.handle.net/10371/62315 | - |
dc.description.abstract | Several tumor animal models have been provided as a tool for developing cancer therapy. Here, we developed rapid, easy-to use, and cost-effective new rat animal model for invasion and metastasis of cancer using genetically k-ras-induced rat kidney cells (RK3E-ras). We observed tumor as early as 3 days after injection of RK3E-ras cells in subcutaneous of Sprague–Dawley rats. Tumor size and volume were increased exponentially for 2 weeks. The tail vein injected rats obtained the lethal infiltration in the lung within 2 weeks. This tumor animal model has great potential for studying cancer processes and short-term screening of variable cancer therapy strategy. | en |
dc.language.iso | en | en |
dc.publisher | Elsevier | en |
dc.subject | RK3E | en |
dc.subject | k-ras | en |
dc.subject | Tumor model | en |
dc.subject | Sprague–Dawley rat | en |
dc.title | Rapid induction of malignant tumor in Sprague-Dawley rats by injection of RME-ras cells | en |
dc.type | Article | en |
dc.contributor.AlternativeAuthor | 박주철 | - |
dc.contributor.AlternativeAuthor | 김수아 | - |
dc.contributor.AlternativeAuthor | 김현우 | - |
dc.contributor.AlternativeAuthor | 김도경 | - |
dc.contributor.AlternativeAuthor | 김수관 | - |
dc.contributor.AlternativeAuthor | 강동완 | - |
dc.contributor.AlternativeAuthor | 김시욱 | - |
dc.contributor.AlternativeAuthor | 안상건 | - |
dc.contributor.AlternativeAuthor | 연정훈 | - |
dc.identifier.doi | 10.1016/j.canlet.2005.04.003 | - |
- Appears in Collections:
- Files in This Item:
- There are no files associated with this item.
Item View & Download Count
Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.