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High b-value diffusion (b = 3000 s/mm2) MR imaging in cerebral gliomas at 3T: visual and quantitative comparisons with b = 1000 s/mm2
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Seo, H. S. | - |
dc.contributor.author | Chang, K.-H. | - |
dc.contributor.author | Na, D. G. | - |
dc.contributor.author | Kwon, B. J. | - |
dc.contributor.author | Lee, D. H. | - |
dc.date.accessioned | 2010-04-07T07:42:05Z | - |
dc.date.available | 2010-04-07T07:42:05Z | - |
dc.date.issued | 2007-12-11 | - |
dc.identifier.citation | AJNR Am J Neuroradiol. 2008 ;29(3):458-63. | en |
dc.identifier.issn | 1936-959X (Electronic) | - |
dc.identifier.issn | 0195-6108 (Print) | - |
dc.identifier.uri | https://hdl.handle.net/10371/62644 | - |
dc.description.abstract | BACKGROUND AND PURPOSE: High b-value diffusion-weighted imaging (DWI) provides different features not appreciated at lower b-value and have been recently studied in several clinical issues. The purpose of this study was to assess whether DWI at b = 3000 s/mm(2) is more useful in discriminating high-grade and low-grade gliomas than DWI at b = 1000 s/mm(2) at 3T. MATERIALS AND METHODS: DWIs at both b = 1000 and 3000 s/mm(2) were performed at 3T in 62 patients, 49 high-grade gliomas (20 World Health Organization [WHO] grade III and 29 grade IV) and 13 low-grade gliomas (13 grade II). Visual assessments based on 5-point scaled evaluations, receiver operating characteristic (ROC) curve analysis, and quantitative assessment based on DWI signal intensity (SI) ratio (tumor SI/normal SI) and apparent diffusion coefficient (ADC) values were compared between DWIs at b = 1000 and 3000 s/mm(2). RESULTS: By visual assessment, DWI at b = 3000 s/mm(2) showed more conspicuous hyperintensity in high-grade gliomas and hypointensity in low-grade gliomas than DWI at b = 1000 s/mm(2). Sensitivity and specificity at b = 3000 s/mm(2) were higher than at b = 1000 s/mm(2) (83.7%, 84.6% vs 69.4%, 76.9%, respectively). Quantitative assessments showed that mean SI ratio of high-grade gliomas was significantly higher than that of low-grade gliomas at both b-values. The mean ADC value of high-grade gliomas was significantly lower than that of low-grade gliomas at both b-values. The difference between the SI ratios of high-grade and low-grade gliomas was significantly larger at b = 3000 s/mm(2) than at b = 1000 s/mm(2). CONCLUSION: DWI at b = 3000 s/mm(2) is more useful than DWI at b = 1000 s/mm(2) in terms of discriminating high-grade and low-grade gliomas at 3T. | en |
dc.language.iso | en | en |
dc.publisher | American Society of Neuroradiology | en |
dc.subject | Adolescent | en |
dc.subject | Adult | en |
dc.subject | Aged | en |
dc.subject | Brain/*pathology | en |
dc.subject | Brain Neoplasms/*diagnosis | en |
dc.subject | Child | en |
dc.subject | Diffusion Magnetic Resonance Imaging/*methods | en |
dc.subject | Female | en |
dc.subject | Glioma/*diagnosis | en |
dc.subject | Humans | en |
dc.subject | Image Enhancement/*methods | en |
dc.subject | Image Interpretation, Computer-Assisted/*methods | en |
dc.subject | Male | en |
dc.subject | Middle Aged | en |
dc.subject | Reproducibility of Results | en |
dc.subject | Sensitivity and Specificity | en |
dc.title | High b-value diffusion (b = 3000 s/mm2) MR imaging in cerebral gliomas at 3T: visual and quantitative comparisons with b = 1000 s/mm2 | en |
dc.type | Article | en |
dc.identifier.doi | 10.3174/ajnr.A0842 | - |
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