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Optimization of the contrast mixture ratio for simultaneous direct MR and CT arthrography: an in vitro study
DC Field | Value | Language |
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dc.contributor.author | Choi, Ja Young | - |
dc.contributor.author | Kang, Heung Sik | - |
dc.contributor.author | Hong, Sung Hwan | - |
dc.contributor.author | Lee, Joon Woo | - |
dc.contributor.author | Kim, Na Ra | - |
dc.contributor.author | Jun, Woo Sun | - |
dc.contributor.author | Moon, Sung Gyu | - |
dc.contributor.author | Choi, Jung Ah | - |
dc.date.accessioned | 2010-04-08T23:32:33Z | - |
dc.date.available | 2010-04-08T23:32:33Z | - |
dc.date.issued | 2008-11-29 | - |
dc.identifier.citation | Korean J Radiol 2008;9(6):520-525 | en |
dc.identifier.issn | 1229-6929 (Print) | - |
dc.identifier.uri | https://hdl.handle.net/10371/62742 | - |
dc.description.abstract | OBJECTIVE: This study was designed to determine the optimal mixture ratio of gadolinium and iodinated contrast agent for simultaneous direct MR arthrography and CT arthrography. MATERIALS AND METHODS: An in vitro study was performed utilizing mixtures of gadolinium at six different concentrations (0.625, 1.25, 2.5, 5.0, 10 and 20 mmol/L) and iodinated contrast agent at seven different concentrations (0, 12.5, 25, 37.5, 50, 75 and 92-99.9%). These mixtures were placed in tissue culture plates, and were then imaged with CT and MR (with T1-weighted sequences, proton-density sequences and T2-weighted sequences). CT numbers and signal intensities were measured. Pearson's correlation coefficients were used to assess the correlations between the gadolinium/iodinated contrast agent mixtures and the CT numbers/MR signal intensities. Scatter diagrams were plotted for all gadolinium/iodinated contrast agent combinations and two radiologists in consensus identified the mixtures that yielded the optimal CT numbers and MR signal intensities. RESULTS: The CT numbers showed significant correlation with iodinated contrast concentrations (r = 0.976, p < 0.001), whereas the signal intensities as measured on MR images showed a significant correlation with both gadolinium and iodinated contrast agent concentrations (r = -484 to -0.719, p < 0.001). A review of the CT and MR images, graphs, and scatter diagram of 42 combinations of the contrast agent showed that a concentration of 1.25 mmol/L gadolinium and 25% iodinated contrast agent was the best combination for simultaneous CT and MR imaging. CONCLUSION: A mixture of 1.25 mmol/L gadolinium and 25% iodinated contrast agent was found to be optimal for simultaneous direct MR arthrography and CT arthrography. | en |
dc.language.iso | en | en |
dc.publisher | Korean Radiological Society | en |
dc.subject | Contrast Media/*administration & dosage | en |
dc.subject | Gadolinium/administration & dosage/*diagnostic use | en |
dc.subject | Iohexol/administration & dosage/*analogs & derivatives/diagnostic use | en |
dc.subject | Meglumine/administration & dosage/*diagnostic use | en |
dc.subject | Organometallic Compounds/administration & dosage/*diagnostic use | en |
dc.subject | Phantoms, Imaging | en |
dc.subject | Arthrography | - |
dc.subject | Magnetic Resonance Imaging | - |
dc.subject | Tomography, X-Ray Computed | - |
dc.title | Optimization of the contrast mixture ratio for simultaneous direct MR and CT arthrography: an in vitro study | en |
dc.type | Article | en |
dc.contributor.AlternativeAuthor | 최자영 | - |
dc.contributor.AlternativeAuthor | 강흥식 | - |
dc.contributor.AlternativeAuthor | 홍성환 | - |
dc.contributor.AlternativeAuthor | 이준우 | - |
dc.contributor.AlternativeAuthor | 김나라 | - |
dc.contributor.AlternativeAuthor | 전우선 | - |
dc.contributor.AlternativeAuthor | 문성규 | - |
dc.contributor.AlternativeAuthor | 최정아 | - |
dc.identifier.doi | 10.3348/kjr.2008.9.6.520 | - |
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