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Comorbidity in disease-free survivors of cervical cancer compared with the general female population
Cited 24 time in
Web of Science
Cited 25 time in Scopus
- Authors
- Issue Date
- 2008-08-21
- Publisher
- Karger
- Citation
- Oncology. 2008;74(3-4):207-15. Epub 2008 Aug 20.
- Keywords
- Case-Control Studies ; Comorbidity ; Disease-Free Survival ; Female ; Humans ; Middle Aged ; Quality of Life ; Questionnaires ; Risk Factors ; Sickness Impact Profile ; Uterine Cervical Neoplasms/*epidemiology/therapy ; Survivors
- Abstract
- OBJECTIVES: We aimed to investigate the prevalence of comorbidities in cervical cancer survivors compared with the general population and to identify risk factors and impact on their quality of life (QoL). METHODS: 860 female cervical cancer survivors enrolled at six tertiary hospitals and 994 women from the general population were surveyed on current comorbidities and QoL (EORTC QLQ-C30 and QLQ-CX24). RESULTS: Compared with the general female population, the cervical cancer survivors reported higher prevalence of comorbidities (0.93 +/- 2.91 vs. 0.37 +/- 0.67, p < 0.01), significantly more heart disease (adjusted odds ratio (aOR), 2.64; 95% confidence interval (CI), 1.38-5.07), liver disease (aOR, 3.29; 95% CI, 1.54-7.02), hypertension (aOR, 1.72; 95% CI, 1.30-2.27), gastrointestinal disease (aOR, 1.79; 95% CI, 1.37-2.33) and musculoskeletal disease (aOR, 1.94; 95% CI, 1.45-2.59). Heart and renal disease significantly influenced QoL in many subscales. Patients with diabetes or cerebrovascular disease had an increased likelihood of sexual problems. CONCLUSIONS: The cervical cancer survivors had more comorbidities than the general population, and that in turn affected their QoL. Vigilant follow-up of comorbidities should be incorporated into in the care of cancer survivors.
- ISSN
- 1423-0232 (Electronic)
1423-0232 (Linking)
- Language
- English
- URI
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18714169
http://content.karger.com/ProdukteDB/produkte.asp?Aktion=ShowPDF&ArtikelNr=000151368&Ausgabe=240006&ProduktNr=223857&filename=000151368.pdf
https://hdl.handle.net/10371/63104
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