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Chronotype distribution in bipolar I disorder and schizophrenia in a Korean sample

Cited 79 time in Web of Science Cited 85 time in Scopus
Authors
Ahn, Yong Min; Chang, Jaeseung; Joo, Yeon Ho; Kim, Seong Chan; Lee, Kyu Young; Kim, Yong Sik
Issue Date
2008-02-15
Publisher
Wiley-Blackwell
Citation
Bipolar Disord. 2008 ;10(2):271-5.
Keywords
AdultAmbulatory CareAsian Continental Ancestry Group/*statistics & numerical dataBipolar Disorder/diagnosis/*ethnology/therapyChronobiology Disorders/diagnosis/*ethnologyDiagnostic and Statistical Manual of Mental DisordersFemaleHumansMalePrevalenceQuestionnairesRetrospective StudiesSchizophrenia/diagnosis/*ethnology/therapySchizophrenia/diagnosis/*ethnology/therapy
Abstract
Objectives: Although a broad range of circadian rhythm variations have been reported, analyses of chronotypes in bipolar I disorder (BDI) and schizophrenia are rare. The present study aimed to investigate specific chronotype patterns in BDI and schizophrenia compared with healthy subjects. METHODS: All patients were clinically stable and recruited from the outpatient clinics of Seoul National University Hospital. They were diagnosed according to DSM-IV criteria. 'Morningness/eveningness', a chronotype correlated with circadian phase, was evaluated using the Composite Scale of Morningness (CSM) among 92 patients with BDI, 113 patients with schizophrenia (SZ), and 95 control individuals. RESULTS: The CSM scores were significantly correlated with age in the control group, but a significant correlation with age was not observed in the schizophrenia or BDI groups. After controlling for age, there were significant differences between the BDI and control groups. The SZ patients did not differ from the BDI or control groups. CONCLUSIONS: In this Korean sample, patients with BDI showed a significantly greater preference for 'eveningness' (including delayed sleep timing) than control individuals. The influences of pharmacotherapy or clinical status on CSM scores need to be clarified.
ISSN
1398-5647 (Print)
Language
English
URI
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18271906

http://hdl.handle.net/10371/63129
DOI
https://doi.org/10.1111/j.1399-5618.2007.00573.x
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College of Medicine/School of Medicine (의과대학/대학원)Psychiatry (정신과학전공)Journal Papers (저널논문_정신과학전공)
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