SHERP

만성간질환에 수반되는 신사구체병변에 관한 병리학적 검토와 인과관계
Glomerulopathies associated with Chronic Hepatitis ---Histological Reapprasal of Glomerular Lesions

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Authors
김용일; 이정빈; 이환종
Issue Date
1977-06
Publisher
서울대학교 의과대학
Citation
Seoul J Med 1977;18(2):106-116
Abstract
In order to verify the immunologic mechanism in
glornerulopathies following viral hepatitis in Korea.
a light microscopic examination was carried out on 9
cases of glomerulopathy associated with histologically
or clinically proven chronic and subsiding viral [tepatitis.
Among the nine glomerular alterations were 6 cases
of membrana-proliferative glomerulonephritis. 2 cases of membraneous glomerulopathy and 1 case of sclerosing
glomerulonephritis probably resulting from mernbraneous
glomerulopathy. Of the five liver needle
biopsies 3 were chronic aggressive hepatitis, 1 subsiding
acute viral hepatitis with residual fibrosis and
micronodular cirrhosis of the liver.
With relatively high incidence of membrano-proliferative
glomerulonephritis among Koreans, seemingly
reflected in part by the influence of serum hepatitis,
especially with deposit of HBAg-Ab complexes, it is
assumed that viral hepatitis is supposed to play an
important role in the pathogenesis of glomerulonephritis
in Korea.
Also a discussion is made on that possibility of
similar immune injury to the glomerular structures as
shown in this investigation may replace the original
concept of cirrhotic glomerulosclerosis.
Language
Korean
URI
http://hdl.handle.net/10371/6631
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Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Dept. of Medicine (의학과)The Seoul Journal of MedicineThe Seoul Journal of Medicine Vol. 18 No.2 (1977)
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