위의 경계 영역병변(이형상피병변)의 병리학적 특성
Borderline Lesion(Atypical Epithelial Lesion) of the Stomach

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김용일; 박효숙; 김우호
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서울대학교 의과대학
Seoul J Med 1977;18(4):213-220
atypical epithelial lesion of the stomach were examined
with authors' modified histo-topographic reconst·
ruction method, and their pathologic characteristics
were discussed along with its histogenesis.
Five out of 7 cases were operated for either early
or advanced carcinoma of the stomach, and only two
were preoperatively diagnosed by endoscopic biopsy
and radiological studies. Average age of the cases was
50.6 years, and majority were found in lower portion
of stomach and mostly single in number. The lesions
were all under 2.0 em in diameter, ranging from O. 5
em to 2. Oem. Macroscopically, they were sessile, poly
paid, global and often mulberry-shaped, but 3 were
made of flat and/or slightly depressed lesions. Cellular
atypism of grade 1 comprised the bulk, with
more prominent nuclear stratification and mitotic figures
in the basal portion where they accompanied
verrucous gastritis. cystic dilatation or intestinal
metaplastic changes of proper glands as their underlying
disorders below the lesion. And adjacent gastric
mucosa represented a diffuse form of severe metaplastic gastritis.
Those figures support that the borderline lesion may
develop as a sequential step of dedifferentiated metaplastic
gastritis during a reparative process of repeated
mucosal erosions of the chronic gastritis.
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College of Medicine/School of Medicine (의과대학/대학원)Dept. of Medicine (의학과)The Seoul Journal of MedicineThe Seoul Journal of Medicine Vol. 18 No.4 (1977)
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