Publications
Detailed Information
Central skull base lymphoma in children: MR and CT features
Cited 19 time in
Web of Science
Cited 18 time in Scopus
- Authors
- Issue Date
- 2008-06-19
- Publisher
- Springer Verlag
- Citation
- Pediatr Radiol. 38(8):863-867
- Keywords
- Child ; Child, Preschool ; Female ; Humans ; Lymphoma/*diagnosis ; Magnetic Resonance Imaging/*methods ; Male ; Skull Base Neoplasms/*diagnosis ; Tomography, X-Ray Computed/*methods
- Abstract
- BACKGROUND: Central skull base tumours are rare in children. OBJECTIVE: To characterize the imaging features of central skull base lymphoma in children to aid its diagnosis. MATERIALS AND METHODS: The authors reviewed the CT findings (available in three patients) and MR findings (available in four patients) in four patients (three boys, one girl; age 2-12 years) with pathologically proven lymphoma (two with Burkitt lymphoma, two with B-cell lymphoma) involving the central skull base. Tumour location and extent, MRI signal intensities, noncontrast CT attenuation, patterns of enhancement, and changes in adjacent structures were evaluated. RESULTS: All four tumours involved the sphenoid bone. In three patients, the tumour extended to the ethmoid sinus and both cavernous sinuses. All lesions were isointense solid masses on T2-weighted images and showed avid enhancement, except for one lesion with a focal necrosis. All tumours were associated with adjacent dural thickening. Non-contrast CT showed highly attenuating masses and permeative bone destruction in the central skull base. CONCLUSION: Lymphoma involving the central skull base in children is visualized as an isointense mass on T2-weighted MRI with marked contrast enhancement and adjacent dural thickening, and as a highly attenuating mass on noncontrast CT with permeative or erosive bone destruction patterns.
- ISSN
- 0301-0449 (Print)
- Language
- English
- URI
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18560821
http://www.springerlink.com/content/x82773545hq08855/fulltext.pdf
https://hdl.handle.net/10371/67845
- Files in This Item:
- There are no files associated with this item.
- Appears in Collections:
Item View & Download Count
Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.