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Integration of a nanoporous platinum thin film into a microfluidic system for non-enzymatic electrochemical glucose sensing

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Authors
Joo, Segyeong; Park, Sejin; Chung, Taek Dong; Kim, Hee Chan
Issue Date
2007-03-21
Publisher
The Japan Society of Analytical Chemistry / The Japan Society for Analytical Chemistry
Citation
Anal Sci. 2007, 23(3):277-281
Keywords
ElectrochemistryEnzymesGlucose/*analysisMicrofluidic Analytical Techniques/*instrumentationNanotechnology/*instrumentationPlatinum/*chemistryPorosity
Abstract
In this paper, we describe an amperometric-type enzymeless glucose sensing system based on a nanoporous platinum (Pt) electrode embedded in a microfluidic chip. This microchip system is comprised of a microfluidic transport channel network and a miniaturized electrochemical cell for nonenzymatic glucose sensing. Sample and buffer solutions were transferred to the cell by programmed electroosmotic flow (EOF). A nanoporous Pt electrode with the roughness factor of 200.6 was utilized to determine glucose concentrations in phosphate buffered saline (PBS) by the direct oxidation of glucose, without any separation process. The sensitivity of the developed system is 1.65 microA cm-2 mM-1 in the glucose concentration range from 1-10 mM in PBS.
ISSN
0910-6340 (Print)
Language
English
URI
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17372368

http://hdl.handle.net/10371/68470
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College of Medicine/School of Medicine (의과대학/대학원)Biomedical Engineering (의공학전공)Journal Papers (저널논문_의공학전공)
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