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Antimicrobial Efficacy of a Polymeric Chlorhexidine Release Device Using In Vitro Model of Enterococcus faecalis Dentinal Tubule Infection
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Yoon | - |
dc.contributor.author | Han, Seung Hyun | - |
dc.contributor.author | Hong, Sang-Hee | - |
dc.contributor.author | Lee, Jin-Kyung | - |
dc.contributor.author | Ji, Hye | - |
dc.contributor.author | Kum, Kee-Yeon | - |
dc.date.accessioned | 2010-07-23 | - |
dc.date.available | 2010-07-23 | - |
dc.date.issued | 2008-07 | - |
dc.identifier.citation | Journal of Endodontics 2008;34(7):855-858 | en |
dc.identifier.issn | 0099-2399 | - |
dc.identifier.uri | https://hdl.handle.net/10371/68665 | - |
dc.description.abstract | This study aimed to assess the antimicrobial efficacy of a novel polymeric chlorhexidine-controlled release device as an intracanal medicament. One hundred cylindrical dentin blocks prepared from human single-rooted teeth were inoculated with Enterococcus faecalis for 3 weeks. The intracanal medicaments tested were calcium hydroxide, a polymeric chlorhexidine-controlled release device (PCRD), a polymeric controlled release device without chlorhexidine (CHx), 0.2% CHx solution, and sterile saline. Dentin samples (at 200-μm and 400-μm depths) were collected from the medicated canal lumens after 1 week of medication with sterile LightSpeed files and placed in growth medium. Bacterial growth was assessed spectrophotometrically by analysis of optical density (OD) after 24 hours of incubation. The OD values at both depths were significantly lower in the PCRD group than in the other experimental groups (P < .001). These results indicate that a PCRD can be an effective intracanal medicament against E. faecalis. | en |
dc.description.sponsorship | This work was supported by the Korea Research Foundation
Grant funded by the Korean Government (MOEHRD, Basic Research Promotion Fund, KRF-2007-314-E00186) and grant 03-2007-0090 from the Seoul National University Dental Hospital Research Fund. | en |
dc.language.iso | en | en |
dc.publisher | Elsevier | en |
dc.subject | Antimicrobial efficacy | en |
dc.subject | cylindrical dentin block | en |
dc.subject | Enterococcus faecalis | en |
dc.subject | optical density | en |
dc.subject | polymeric chlorhexidine-controlled release device | en |
dc.title | Antimicrobial Efficacy of a Polymeric Chlorhexidine Release Device Using In Vitro Model of Enterococcus faecalis Dentinal Tubule Infection | en |
dc.type | Article | en |
dc.contributor.AlternativeAuthor | 이윤 | - |
dc.contributor.AlternativeAuthor | 한승현 | - |
dc.contributor.AlternativeAuthor | 홍상희 | - |
dc.contributor.AlternativeAuthor | 이진경 | - |
dc.contributor.AlternativeAuthor | 지혜 | - |
dc.contributor.AlternativeAuthor | 금기연 | - |
dc.identifier.doi | 10.1016/j.joen.2008.04.008 | - |
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