S-Space College of Medicine/School of Medicine (의과대학/대학원) Dept. of Medicine (의학과) The Seoul Journal of Medicine The Seoul Journal of Medicine Vol. 31 No.2 (1990)
Retrogressive Changes of Dental Lamina Rests in Human Fetal Maxilla
사람태아 상악골내에 보이는 치제상피잔사의 퇴행성 변화
- Lee, Suk Keun; Lim, Chang Yun; Chi, Je G.
- Issue Date
- Seoul J Med, Vol.31 No.2, pp. 107-116
- In order to elucidate the retrogressive changes of dental lamina rest (DLR) in
human fetuses, 232 human maxillas were examined histologically. In 227 maxillas prepared
for light microscopy, the dental laminas were composed of three portions: the dental lamina
ridge, the primary dental lamina, and the secondary dental lamina. All of the dental laminas
were separated into numerous small islets, i.e., dental lamina rests (DLRs). DLRs of the
dental lamina ridge especially showed heavy keratinization in their center. Almost all of the
DLRs from the primary and secondary dental laminas became atrophic and degenerative.
While abundant capillary proliferation was observed in the vicinity of the DLRs, occasionally
small numbers of inflammatory cells infiltrated around the atrophic DLRs. In five cases
prepared for electron-microscopy, the degenerating DLRs showed tonofilaments which were
reduced in number and considerably aberrant. The basal laminas of the degenerating epithelial
cells were gradually destroyed with the increase of gestational age, and a few inflammatory
cells containing a large quantity of Iysozome adhered to the DLR to destroy the entire
basal lamina directly. In this study we confirmed that the DLRs were resorbed by the
processes of both self-degeneration and the cytotoxic reaction of inflammatory cells.