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The Prevalence of and Risk Factors for Barrett`s Esophagus in a Korean Population A Nationwide Multicenter Prospective Study

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Authors
Park, Jong-Jae; Kim, Jae Woo; Kim, Hyun Jin; Chung, Moon Gi; Baik, Gwang Ho; Nam, Su Youn; Ko, Byung Sung; Kim, Byeong Gwan; Choi, Youn Seon; Chung, In-Sik; Jung, Hyun Chae; Park, Soo-Heon; Kim, Nayoung; Cho, Mee-Yon; Kim, Jin Il; Joo, Moon Kyung; Kim, Ji Won; Jang, Jae-Young; Seo, Kang Seok; Nah, Byung Kyu; Park, Seon Mee
Issue Date
2009-12
Publisher
LIPPINCOTT WILLIAMS & WILKINS
Citation
JOURNAL OF CLINICAL GASTROENTEROLOGY; Vol.43 10; 907-914
Keywords
Barrett esophagusprevalencerisk factorsreflux symptom
Abstract
Objective: The aim of this study was to evaluate the prevalence of Barrett`s esophagus (BE) in the general Korean population by evaluating, screening esophagogastroduodenoscopy. In addition. the risk factors for BE were identified. Method: An esophagogastroduodenoscopy examination was performed in 25,536 subjects who had Upper endoscopy screening from January 2006 to July 2006. Results: Two hundred and fifteen Subjects were confirmed to have BE by pathology. thus the prevalence of BE was calculated to be 0.84%,. The endoscopic findings were subdivided into 2 groups: BE Without reflux esophagitis (RE). which included 167 (77.7%), and BE with R E, which included 48 (22.3%). The analysis of symptoms showed that only 60.1% of the subjects with BE had reflux symptoms. Chest pain [odds ratio (OR): 1.48, 95% confidence interval (0): 1.04-2.11] and epigastric soreness (OR: 1.42, 95% Cl: 1.05-1.93) were found more frequently in the Subjects with BE compared with the normal Subjects. The multivariate analysis showed that the risk factors for all subjects with BE were a male sex (OR: 1.81 95% Cl: 1.32-2.50). nonsteroidal anti-inflammatory drug use (OR: 2.02, 95%, Cl: 1.28-3.20). hiatal hernia (OR: 5.66. 95% Cl: 3.70-8.66), and an age >= 60 compared with in age < 40 (OR: 1.81. 95% Cl: 1.07-3.09). There was no significant difference associated with RE. Conclusions: The prevalence of BE in Korean patients presenting for a routine health check-up was 0.84% lower than reported in Western countries. Among the subjects with BE 77.7% did not have endoscopic erosions and there were no reflux symptoms in 39.9%. These results suggest that regular endoscopic screening with a high index of suspicion is necessary for the diagnosis of BE.
ISSN
0192-0790
Language
English
URI
http://hdl.handle.net/10371/76424
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College of Medicine/School of Medicine (의과대학/대학원)Internal Medicine (내과학전공)Journal Papers (저널논문_내과학전공)
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