Publications
Detailed Information
Cyclooxygenase-2 Expression in Cervical Intraepithelial Neoplasia
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Kidong | - |
dc.contributor.author | Jeon, Yong-Tark | - |
dc.contributor.author | Park, In-Ae | - |
dc.contributor.author | Kim, Jae Weon | - |
dc.contributor.author | Kang, Soon-Beom | - |
dc.contributor.author | Song, Yong-Sang | - |
dc.contributor.author | Lee, Hyo-Pyo | - |
dc.contributor.author | Park, Noh-Hyun | - |
dc.date.accessioned | 2012-05-30T05:56:47Z | - |
dc.date.available | 2012-05-30T05:56:47Z | - |
dc.date.issued | 2009 | - |
dc.identifier.citation | Annals of the New York Academy of Sciences; Vol.1171 ; 111-115 | ko_KR |
dc.identifier.issn | 0077-8923 | - |
dc.identifier.uri | https://hdl.handle.net/10371/76620 | - |
dc.description.abstract | To evaluate the role of cyclooxygenase (COX)-2 during cervical carcinogenesis, we investigated COX-2 expression in the dysplastic epithelium and stromal cells of cervical intraepithelial neoplasia (CIN). Immunohistochemical analysis with COX-2 antibody was performed on 148 paraffin-embedded tissue specimens of patients who were diagnosed as CIN in our institute. COX-2 expression was evaluated separately in the dysplastic epithelium and stromal cells of CIN. The relationships between COX-2 expression and clinicopathologic variables were examined. For the dysplastic epithelium, COX-2 expression was negative in 137 (92.6%) and positive in 11 (7.4%) specimens. For the stromal cells, COX-2 expression was negative in all specimens. The COX-2 expression in dysplastic epithelium was higher in older (P = 0.038) or postmenopausal (P = 0.025) women. In conclusion, COX-2 expression was observed only in the dysplastic epithelium but not in the stromal cells of CIN. The COX-2 expression in dysplastic epithelium was associated with age and menopausal status. | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | BLACKWELL PUBLISHING | ko_KR |
dc.subject | cyclooxygenase-2 | ko_KR |
dc.subject | cervical intraepithelial neoplasia (CIN) | ko_KR |
dc.subject | menopause | ko_KR |
dc.subject | stromal cells | ko_KR |
dc.subject | epithelium | ko_KR |
dc.subject | age factors | ko_KR |
dc.title | Cyclooxygenase-2 Expression in Cervical Intraepithelial Neoplasia | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 김기동 | - |
dc.contributor.AlternativeAuthor | 전용탁 | - |
dc.contributor.AlternativeAuthor | 박인애 | - |
dc.contributor.AlternativeAuthor | 김재원 | - |
dc.contributor.AlternativeAuthor | 박노현 | - |
dc.contributor.AlternativeAuthor | 강순범 | - |
dc.contributor.AlternativeAuthor | 이효표 | - |
dc.contributor.AlternativeAuthor | 송용상 | - |
dc.identifier.doi | 10.1111/j.1749-6632.2009.04724.x | - |
dc.citation.journaltitle | NATURAL COMPOUNDS AND THEIR ROLE IN APOPTOTIC CELL SIGNALING PATHWAYS | - |
dc.description.citedreference | Subbaramaiah K, 2007, CANCER RES, V67, P3976, DOI 10.1158/0008-5472.CAN-06-4273 | - |
dc.description.citedreference | Dursun P, 2007, INT J GYNECOL CANCER, V17, P164, DOI 10.1111/j.1525-1438.2007.00798.x | - |
dc.description.citedreference | Lee TS, 2007, ANN NY ACAD SCI, V1095, P143, DOI 10.1196/annals.1397.018 | - |
dc.description.citedreference | Hardy DB, 2006, MOL ENDOCRINOL, V20, P2724, DOI 10.1210/me.2006-0112 | - |
dc.description.citedreference | Kang SB, 2006, CANCER LETT, V237, P305, DOI 10.1016/j.canlet.2005.06.027 | - |
dc.description.citedreference | Kim JY, 2005, GYNECOL ONCOL, V97, P337, DOI 10.1016/j.ygyno.2004.09.012 | - |
dc.description.citedreference | Dai YM, 2005, GYNECOL ONCOL, V97, P96, DOI 10.1016/j.ygyno.2004.12.020 | - |
dc.description.citedreference | Jeon YT, 2004, CANCER EPIDEM BIOMAR, V13, P1538 | - |
dc.description.citedreference | Sheehan KM, 2004, EUR J GASTROEN HEPAT, V16, P619, DOI 10.1097/01.meg.000108313.52416.38 | - |
dc.description.citedreference | Seo SS, 2004, GYNECOL ONCOL, V92, P927, DOI 10.1016/j.ygyno.2003.11.055 | - |
dc.description.citedreference | Lin H, 2004, INT J GYNECOL CANCER, V14, P311 | - |
dc.description.citedreference | Farley J, 2004, GYNECOL ONCOL, V92, P596, DOI 10.1016/j.ygyno.2003.10.052 | - |
dc.description.citedreference | Kim MH, 2003, GYNECOL ONCOL, V90, P83, DOI 10.1016/S0090-8258(03)00224-5 | - |
dc.description.citedreference | Kawada M, 2003, DIGESTION, V67, P20, DOI 10.1159/000069708 | - |
dc.description.citedreference | Ferrandina G, 2002, BRIT J CANCER, V87, P1145, DOI 10.1038/sj.bjc.6600578 | - |
dc.description.citedreference | Kim YB, 2002, CANCER, V95, P531, DOI 10.1002/cncr.10684 | - |
dc.description.citedreference | Surh YJ, 2001, MUTAT RES-FUND MOL M, V480, P243, DOI 10.1016/S0027-5107(01)00183-X | - |
dc.description.citedreference | Williams CS, 2000, J CLIN INVEST, V105, P1589 | - |
dc.description.citedreference | Prescott SM, 2000, J CLIN INVEST, V105, P1511 | - |
dc.description.citedreference | Williams CS, 1999, ONCOGENE, V18, P7908 | - |
dc.description.citedreference | Tjalma W, 1999, AM J OBSTET GYNECOL, V181, P554 | - |
dc.description.citedreference | Williams C, 1999, ANN NY ACAD SCI, V889, P72 | - |
dc.description.citedreference | Kinzler KW, 1998, SCIENCE, V280, P1036 | - |
dc.description.citedreference | Oshima M, 1996, CELL, V87, P803 | - |
dc.description.citedreference | MUNGER K, 1992, CANCER SURV, V12, P197 | - |
dc.description.tc | 1 | - |
- Appears in Collections:
- Files in This Item:
- There are no files associated with this item.
Item View & Download Count
Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.