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신경신호 측정을 위한 SPR(표면플라즈몬공명) 시스템 개발 : Development of Surface Plasmon Resonance(SPR) system for detecting neural signals
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김신애 | - |
dc.contributor.author | 박형원 | - |
dc.contributor.author | 김성준 | - |
dc.date.accessioned | 2009-08-25T02:53:27Z | - |
dc.date.available | 2009-08-25T02:53:27Z | - |
dc.date.issued | 2007-05-11 | - |
dc.identifier.citation | 제35회 대한의용생체공학회 춘계학술대회, 전북대학교, 2007년 5월 11-12일 | en |
dc.identifier.uri | https://hdl.handle.net/10371/7674 | - |
dc.description.abstract | This study aims to develop a new effective
extracellular recording system for detecting neural signal using Surface Plasmon Resonance (SPR). The SPR can directly detect electrochemical signals at the metal-electrolyte interface. In addition, this method has no time limit in measurement and no artifact noise during electrical stimulation compared with conventional electrophysiological methods. However, the low sensitivity of SPR has been known as a problem for detecting a subtle ionic changes like action potentials. To overcome this problem, we improved several parts of a conventional SPR system; i) introduction of a multi-cell photo-detector with a mask, ii) introduction of a ultra-low noise laser diode, iii) electrical shielding of the whole optic system using a custom-made faraday cage. Consequently, evoked Compound Action Potentials (CAPS) from rat sciatic nerves were successfully recorded. These recordings are the first time of detecting neural signal using SPR biosensor. These data indicate that the SPR system can be used as a valuable tool for the study of neural networks. | en |
dc.description.sponsorship | This work was supported by the NBS-ERC (Nano Bioelectronics and System Research Center) of Seoul National University, which is an ERC supported by MIST/KOSEF. | en |
dc.language.iso | ko | - |
dc.publisher | 대한의용생체공학회 = The Korean Society of Medical & Biological Engineering | en |
dc.title | 신경신호 측정을 위한 SPR(표면플라즈몬공명) 시스템 개발 | en |
dc.title.alternative | Development of Surface Plasmon Resonance(SPR) system for detecting neural signals | en |
dc.type | Conference Paper | en |
dc.contributor.AlternativeAuthor | Kim, Shin Ae | - |
dc.contributor.AlternativeAuthor | Baac, Hyoung Won | - |
dc.contributor.AlternativeAuthor | Kim, Sung June | - |
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