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Successful Salvage Unrelated Umbilical Cord Blood Transplantation with Two Units After Engraftment Failure with Single Unit in Severe Aplastic Anemia
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Ji Won | - |
dc.contributor.author | Kang, Hyoung Jin | - |
dc.contributor.author | Kim, Eun Kyung | - |
dc.contributor.author | Shin, Hee Young | - |
dc.contributor.author | Ahn, Hyo Seop | - |
dc.date.accessioned | 2012-06-12T04:16:20Z | - |
dc.date.available | 2012-06-12T04:16:20Z | - |
dc.date.issued | 2009-08 | - |
dc.identifier.citation | JOURNAL OF KOREAN MEDICAL SCIENCE; Vol.24 4; 744-746 | ko_KR |
dc.identifier.issn | 1011-8934 | - |
dc.identifier.uri | https://hdl.handle.net/10371/76991 | - |
dc.description.abstract | Severe aplastic anemia (SAA) patients without an HLA-matched sibling donor need alternative treatment options. Umbilical cord blood transplantation (UCBT) has become an alternative means for treating various diseases, but it has not been proved to be a satisfactory method to treat SAA. Here, we report the case of a girl who underwent successful two-unit UCBT after engraftment failure with a single unit. Two-unit UCBT is proposed to have better engraftment potential and to offer a better chance of survival, according to some reports. Increased cell dose and graft-versus-graft reaction could contribute to these advantages. With this promising result, two-unit UCBT could be an alternative treatment option for patients with SAA without an HLA-matched donor. | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | KOREAN ACAD MEDICAL SCIENCES | ko_KR |
dc.subject | Anemia, Aplastic | ko_KR |
dc.subject | Cord Blood Stem Cell Transplantation | ko_KR |
dc.subject | Two-unit | ko_KR |
dc.title | Successful Salvage Unrelated Umbilical Cord Blood Transplantation with Two Units After Engraftment Failure with Single Unit in Severe Aplastic Anemia | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 이지원 | - |
dc.contributor.AlternativeAuthor | 강형진 | - |
dc.contributor.AlternativeAuthor | 김은규 | - |
dc.contributor.AlternativeAuthor | 신희영 | - |
dc.contributor.AlternativeAuthor | 안효섭 | - |
dc.identifier.doi | 10.3346/jkms.2009.24.4.744 | - |
dc.citation.journaltitle | JOURNAL OF KOREAN MEDICAL SCIENCE | - |
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dc.description.citedreference | Rubinstein P, 1998, NEW ENGL J MED, V339, P1565 | - |
dc.description.citedreference | GLUCKMAN E, 1989, NEW ENGL J MED, V321, P1174 | - |
dc.description.tc | 2 | - |
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