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The impact of insulin sensitisers on lung function in patients with chronic obstructive pulmonary disease and diabetes
DC Field | Value | Language |
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dc.contributor.author | Kim, H. J. | - |
dc.contributor.author | Lee, J. Y. | - |
dc.contributor.author | Jung, H. S. | - |
dc.contributor.author | Kim, D-K. | - |
dc.contributor.author | Yim, J-J. | - |
dc.contributor.author | Yoo, C-G. | - |
dc.contributor.author | Kim, Y. W. | - |
dc.contributor.author | Shim, Y-S. | - |
dc.contributor.author | Lee, C-H. | - |
dc.contributor.author | Han, S. K. | - |
dc.contributor.author | Chung, H. S. | - |
dc.contributor.author | Yang, S-C. | - |
dc.contributor.author | Lee, S-M. | - |
dc.date.accessioned | 2012-06-25T05:20:06Z | - |
dc.date.available | 2012-06-25T05:20:06Z | - |
dc.date.issued | 2010-03 | - |
dc.identifier.citation | INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE; Vol.14 3; 362-367 | ko_KR |
dc.identifier.issn | 1027-3719 | - |
dc.identifier.uri | https://hdl.handle.net/10371/77386 | - |
dc.description.abstract | SETTING: It has been reported that diabetes mellitus (DM) is associated with poor pulmonary function, which could be explained by insulin resistance. OBJECTIVE: To evaluate whether insulin sensitisers (ISs) have beneficial effects on lung function in patients with chronic obstructive pulmonary disease (COPD) and DM. DESIGN: This retrospective study included patients with both COPD and DM who attended Seoul National University Hospital for treatment between 1 January 2000 and 31 August 2007. They were treated with inhalers for COPD and oral hypoglycaemia agents, including ISs or insulin, for DM. The primary outcome was a change in lung function in spirometric examinations. RESULTS: Among 61 patients enrolled, 32 were in the no IS group, while 29 were in the IS group. On multivariable regression analysis, the IS group showed a significantly greater change in forced vital capacity (FVC) than the no IS group (adjusted beta-coefficient 131.9, 95%CI 8.5-255.4, P = 0.04). CONCLUSIONS: Treatment with an IS was independently associated with improvements in FVC in patients with both COPD and DM, compared with treatment without IS. | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | INT UNION AGAINST TUBERCULOSIS LUNG DISEASE (I U A T L D) | ko_KR |
dc.subject | insulin sensitiser | ko_KR |
dc.subject | diabetes | ko_KR |
dc.subject | insulin resistance | ko_KR |
dc.subject | lung function | ko_KR |
dc.subject | chronic obstructive pulmonary disease | ko_KR |
dc.title | The impact of insulin sensitisers on lung function in patients with chronic obstructive pulmonary disease and diabetes | ko_KR |
dc.type | Article | ko_KR |
dc.citation.journaltitle | INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE | - |
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dc.description.tc | 4 | - |
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