Prediction and prevention of preterm birth after cervical conization

Abstract

The introduction of the cervical cancer screening strategy has substantially reduced the incidence of and mortality from invasive cervical cancer.1 This trend has been attributed to early detection and following treatment of pre-invasive cervical lesions, and cervical intraepithelial neoplasia (CIN) is commonly diagnosed in women of reproductive age. Although the fact that the conservative treatment for CIN (including cold knife conization, large loop excision of the transformation zone (LLETZ)/ loop electrosurgical excision procedure (LEEP), laser conization, or ablative therapy) should be effective is the most important issue, subsequent impact of these treatment modalities on future fertility and pregnancy outcome is also a major concerning point in younger women.