Publications
Detailed Information
Mesenchymal stem cells showed the highest potential for the regeneration of injured liver tissue compared with other subpopulations of the bone marrow
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Cho, Kyung-Ah | - |
dc.contributor.author | Ju, Sun-Young | - |
dc.contributor.author | Cho, Su Jin | - |
dc.contributor.author | Jung, Yun-Jae | - |
dc.contributor.author | Seoh, Ju-Young | - |
dc.contributor.author | Ryu, Kyung-Ha | - |
dc.contributor.author | Han, Ho-Seong | - |
dc.contributor.author | Woo, So-Youn | - |
dc.date.accessioned | 2012-06-29T02:33:41Z | - |
dc.date.available | 2012-06-29T02:33:41Z | - |
dc.date.issued | 2009-07 | - |
dc.identifier.citation | CELL BIOLOGY INTERNATIONAL; Vol.33(7); 772-777 | ko_KR |
dc.identifier.issn | 1065-6995 | - |
dc.identifier.uri | https://hdl.handle.net/10371/77898 | - |
dc.description.abstract | We have previously reported that bone marrow cells (BMCs) participate in the regeneration after liver injury. However, it is not established that this is the result of differentiation of hematopoietic stem cells (HSCs), mesenchymal stem cells (MSCs) or the combination of both. We investigated the contribution of each cell fraction to the regenerative process. First, we confirmed that transplanted stem cells migrate directly to injured liver tissue without dispersing to other organs. Next, we divided green fluorescent protein (GFP)-expressing BMCs into three populations as mononuclear cells, MSCs and HSCs. We then compared the engraftment capacity after transplantation of each fraction of cells into liver-injured mice. Of these, the MSCs transplanted group showed the highest GFP fluorescence intensities in liver tissue by flow cytometry analysis and confocal microscopic observation. Furthermore, MSCs showed differentiation potential into hepatocytes when co-cultured with injured liver cells, which suggests that MSCs showed highest potential for the regeneration of injured liver tissue compared with those of the other two cell refractions. (c) 2009 International Federation for Cell Biology. Published by Elsevier Ltd. All rights reserved. | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD | ko_KR |
dc.subject | Mesenchymal stem cells (MSCs) | ko_KR |
dc.subject | Liver injury | ko_KR |
dc.subject | Transplantation | ko_KR |
dc.title | Mesenchymal stem cells showed the highest potential for the regeneration of injured liver tissue compared with other subpopulations of the bone marrow | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 조경아 | - |
dc.contributor.AlternativeAuthor | 주선영 | - |
dc.contributor.AlternativeAuthor | 조수진 | - |
dc.contributor.AlternativeAuthor | 정윤재 | - |
dc.contributor.AlternativeAuthor | 우소윤 | - |
dc.contributor.AlternativeAuthor | 서주영 | - |
dc.contributor.AlternativeAuthor | 한호성 | - |
dc.contributor.AlternativeAuthor | 류경하 | - |
dc.identifier.doi | 10.1016/j.cellbi.2009.04.023 | - |
dc.citation.journaltitle | CELL BIOLOGY INTERNATIONAL | - |
dc.description.citedreference | Chen Y, 2007, J CELL BIOCHEM, V102, P52, DOI 10.1002/jcb.21275 | - |
dc.description.citedreference | Ong SY, 2006, TISSUE ENG, V12, P3477 | - |
dc.description.citedreference | Jung YJ, 2006, STEM CELLS DEV, V15, P687 | - |
dc.description.citedreference | Terai S, 2006, STEM CELLS, V24, P2292, DOI 10.1634/stemcells.2005-0542 | - |
dc.description.citedreference | Talens-Visconti R, 2006, WORLD J GASTROENTERO, V12, P5834 | - |
dc.description.citedreference | Chen Y, 2006, CYTOTHERAPY, V8, P381, DOI 10.1080/14653240600735800 | - |
dc.description.citedreference | Russo FP, 2006, GASTROENTEROLOGY, V130, P1807, DOI 10.1053/j.gastro.2006.01.036 | - |
dc.description.citedreference | Lange C, 2006, WORLD J GASTROENTERO, V12, P2394 | - |
dc.description.citedreference | Hristov M, 2006, MED KLIN, V101, P186 | - |
dc.description.citedreference | Okumoto K, 2006, J GASTROENTEROL, V41, P62, DOI 10.1007/s00535-005-1723-8 | - |
dc.description.citedreference | CAO BQ, 2006, WORLD J GASTROENTERO, V13, P1851 | - |
dc.description.citedreference | CAO BQ, 2006, WORLD J GASTROENTERO, V13, P1854 | - |
dc.description.citedreference | Terai S, 2005, J HEPATO-BILIARY-PAN, V12, P203, DOI 10.1007/s00534-005-0977-0 | - |
dc.description.citedreference | Sato Y, 2005, TRANSPLANT P, V37, P273, DOI 10.1016/j.transproceed.2005.01.035 | - |
dc.description.citedreference | Okumoto K, 2003, BIOCHEM BIOPH RES CO, V304, P691, DOI 10.1016/S0006-291X(03)00637-5 | - |
dc.description.citedreference | Strauer BE, 2002, CIRCULATION, V106, P1913, DOI 10.1161/01.CIR.0000034046.87607.1C | - |
dc.description.citedreference | Morio LA, 2001, TOXICOL APPL PHARM, V172, P44, DOI 10.1006/taap.9133 | - |
dc.description.tc | 11 | - |
- Appears in Collections:
- Files in This Item:
- There are no files associated with this item.
Item View & Download Count
Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.