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Predictive CT findings of malignancy in ground-glass nodules on thin-section chest CT: the effects on radiologist performance

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dc.contributor.authorLee, Hyun Ju-
dc.contributor.authorGoo, Jin Mo-
dc.contributor.authorLee, Chang Hyun-
dc.contributor.authorPark, Chang Min-
dc.contributor.authorPark, Eun-Ah-
dc.contributor.authorLee, Ho Yun-
dc.contributor.authorKim, Kwang Gi-
dc.date.accessioned2012-07-02T05:14:44Z-
dc.date.available2012-07-02T05:14:44Z-
dc.date.issued2009-03-
dc.identifier.citationEUROPEAN RADIOLOGY; Vol.19 3; 552-560ko_KR
dc.identifier.issn0938-7994-
dc.identifier.urihttp://hdl.handle.net/10371/78078-
dc.description.abstractOur purpose was to identify thin-section chest computed tomography (CT) findings of malignancy other than the presence of a solid portion within ground-glass nodules (GGNs) and to evaluate whether the radiologists` performance in determining malignancy can be enhanced with this information. The predictive CT findings of malignancy extracted from the CT findings of 80 GGNs (47 malignant, 33 benign) were a size of > 8 mm [odds ratio (OR), 10.930; P = 0.045] and a lobulated border (OR, 13.769; P = 0.016) for pure GGNs and a lobulated border (OR, 10.200; P = 0.024) for mixed GGNs. Four chest radiologists and five radiology residents participated in the observer performance study with CT of 130 GGNs (67 malignant, 63 benign). Receiver-operating characteristic (ROC) analysis was used to compare radiologists` performances before and after providing these predictive findings. For pure GGNs, mean areas under the curve (A(z)) of all readers without and with CT predictive information were significantly different (0.621 +/- 0.052 and 0.766 +/- 0.055, P < 0.05). For mixed GGNs, the A(z) values achieved without and with predictive information were not significantly different (0.727 +/- 0.064 and 0.764 +/- 0.056, P > 0.05). Information about lesion size and morphological characteristics can enhance radiologists` performance in determining malignancy of pure GGNs.ko_KR
dc.description.sponsorshipThis work was supported by a Korean Research Foundation Grant
funded by the Korean Government (MOEHRD) (#KRF-2005-
E00294).
ko_KR
dc.language.isoenko_KR
dc.publisherSPRINGERko_KR
dc.subjectThin-section chest CTko_KR
dc.subjectLungko_KR
dc.subjectNoduleko_KR
dc.subjectSubsolid noduleko_KR
dc.subjectGround-glass noduleko_KR
dc.titlePredictive CT findings of malignancy in ground-glass nodules on thin-section chest CT: the effects on radiologist performanceko_KR
dc.typeArticleko_KR
dc.contributor.AlternativeAuthor이현주-
dc.contributor.AlternativeAuthor구진모-
dc.contributor.AlternativeAuthor이창현-
dc.contributor.AlternativeAuthor박창민-
dc.contributor.AlternativeAuthor김광기-
dc.contributor.AlternativeAuthor박은아-
dc.contributor.AlternativeAuthor이호윤-
dc.identifier.doi10.1007/s00330-008-1188-2-
dc.citation.journaltitleEUROPEAN RADIOLOGY-
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College of Medicine/School of Medicine (의과대학/대학원)Radiology (영상의학전공)Journal Papers (저널논문_영상의학전공)
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