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Change of skin color after application of topical anesthetic cream

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dc.contributor.authorKim, Hye-One-
dc.contributor.authorKim, Byeong-Gyun-
dc.contributor.authorShin, Jung-Won-
dc.contributor.authorHuh, Sun-Young-
dc.contributor.authorHuh, Chang-Hun-
dc.contributor.authorPark, Kyoung-Chan-
dc.contributor.authorYoun, Sang-Woong-
dc.date.accessioned2012-07-03T00:40:57Z-
dc.date.available2012-07-03T00:40:57Z-
dc.date.issued2009-12-
dc.identifier.citationJOURNAL OF DERMATOLOGICAL TREATMENT; Vol.20, no.6; 376-377ko_KR
dc.identifier.issn0954-6634-
dc.identifier.urihttp://hdl.handle.net/10371/78159-
dc.description.abstractSirs,
Lidocaine/prilocaine cream (EMLA®; Astra
Pharmaceuticals, Sweden) contains 2.5% of lidocaine and 2.5% of prilocaine and is a preparation for topical anesthesia of skin (1). Although the blanching reaction of lidocaine/prilocaine cream is frequently reported (2), the exact causes have not been clarified yet. It may be due to vasoconstrictive effects by active substances or optical scattering effects by hydration of stratum corneum (3). Furthermore, whether lidocaine/prilocaine cream induced the vasoconstriction or vasodilatation of cutaneous vasculature is still controversial (4–7). Since lidocaine/prilocaine cream is applied before laser surgery to treat pigmentary or vascular lesions, it is important to know whether this cream induces pigmentary or vascular changes. The Mexameter®, which measures absorbed and reflected light at wavelengths for hemoglobin (green and red) and melanin (red and near-infrared), was used to measure the color changes caused by lidocaine/prilocaine cream. Skin capacitance (SC), indicating the level of hydration of stratum corneum, was also measured (8).
ko_KR
dc.language.isoenko_KR
dc.publisherInforma Healthcareko_KR
dc.titleChange of skin color after application of topical anesthetic creamko_KR
dc.typeArticleko_KR
dc.contributor.AlternativeAuthor김혜원-
dc.contributor.AlternativeAuthor김병균-
dc.contributor.AlternativeAuthor신정원-
dc.contributor.AlternativeAuthor허선영-
dc.contributor.AlternativeAuthor윤상웅-
dc.contributor.AlternativeAuthor허창훈-
dc.contributor.AlternativeAuthor박경찬-
dc.identifier.doi10.3109/09546630902877923-
dc.citation.journaltitleJOURNAL OF DERMATOLOGICAL TREATMENT-
dc.description.citedreferenceWilder-Smith E, 2003, MICROVASC RES, V66, P68, DOI 10.1016/S0026-2862(03)00020-7-
dc.description.citedreferenceHafner HM, 2003, CLIN HEMORHEOL MICRO, V28, P121-
dc.description.citedreferenceEgekvist H, 1997, ACTA DERM-VENEREOL, V77, P214-
dc.description.citedreferenceSTEWARD DJ, 1993, J PEDIATR, V122, pS21-
dc.description.citedreferenceBJERRING P, 1990, BRIT J ANAESTH, V64, P173-
dc.description.citedreferenceVILLADA G, 1990, DERMATOLOGICA, V181, P38-
dc.description.citedreferenceARENDTNIELSEN L, 1990, ACTA DERM-VENEREOL, V70, P314-
dc.description.citedreferenceBLICHMANN CW, 1988, ACTA DERM-VENEREOL, V68, P284-
dc.description.tc0-
Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Dermatology (피부과학전공)Journal Papers (저널논문_피부과학전공)
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