Publications
Detailed Information
Feasibility of Template-Guided Attenuation Correction in Cat Brain PET Imaging
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Jin Su | - |
dc.contributor.author | Lee, Jae Sung | - |
dc.contributor.author | Park, Min-Hyun | - |
dc.contributor.author | Kim, Kyeong Min | - |
dc.contributor.author | Cheon, Gi Jeong | - |
dc.contributor.author | Moon, Dae Hyuk | - |
dc.contributor.author | Lee, Dong Soo | - |
dc.contributor.author | Chung, June-Key | - |
dc.contributor.author | Song, In Chan | - |
dc.contributor.author | Oh, Seung-Ha | - |
dc.date.accessioned | 2012-07-03T08:24:36Z | - |
dc.date.available | 2012-07-03T08:24:36Z | - |
dc.date.issued | 2010-06 | - |
dc.identifier.citation | MOLECULAR IMAGING AND BIOLOGY; Vol.12 3; 250-258 | ko_KR |
dc.identifier.issn | 1536-1632 | - |
dc.identifier.uri | https://hdl.handle.net/10371/78309 | - |
dc.description.abstract | Purpose: Attenuation correction (AC) is important in quantitative positron emission tomography (PET) imaging of medium-sized animals such as the cat. However, additional time for transmission (TX) scanning and tracer uptake is required in PET studies with animal-dedicated PET scanners because post-injection TX scanning is not available in these systems. The aim of this study was to validate a template-guided AC (TGAC) method that does not require TX PET data for AC in cat 2-deoxy-2-[F-(18)fluoro-D-glucose (FDG) brain PET imaging. Methods: PET scans were acquired using a microPET Focus 120 scanner. TX data were obtained using a (68)Ge point source before the injection of FDG. To generate the attention map (mu-map) template for the TGAC, a target image of emission (EM) PET was selected, and spatial normalization parameters of individual EM data onto the target were reapplied to the corresponding mu-maps. The inverse transformations of the mu-map template into the individual spaces were performed, and the transformed template was forward projected to generate the AC factor. The TGAC method was compared with measured AC (MAC) and calculated AC (CAC) methods using region of interest (ROI) and SPM analyses. Results: The ROI analysis showed that the activity of the TGAC EM PET images strongly correlated with those of the MAC data (y = 0.98x + 0.01, R(2)=0.96). In addition, no significant difference was observed in the SPM analysis. By contrast, the CAC showed a significantly higher uptake in the deep gray regions compared to the MAC (corrected P<0.05). The ROI correlation with MAC was worse than with the TGAC (R(2)=0.84). In SPM analysis for the voxel-wise group comparisons between before and after the induction of deafness, only the TGAC showed equivalent results with the MAC. Conclusions: The TGAC was reliable in cat FDG brain PET studies in terms of compatibility with the MAC method. The TGAC might be a useful option for increasing study throughput and decreasing the probability of subject movement. In addition, it might reduce the possible biological effects of long-term anesthesia on the cat brain in investigations using animal-dedicated PET scanners. | ko_KR |
dc.description.sponsorship | This work was supported by grants from the
World Class University Program (R32-10142), Atomic Energy R&D Program (2008-03852), Basic Atomic Energy Research Institute Program (M20508050002-05B0805-00210, 2008-02334), Nuclear R&D Program (M20702010002-08N0201-00200, 20090078289), and Brain Research Center of the 21st Century Frontier Research Program (M103KV010014-04K2201-01400) through the Korea Science and Engineering Foundation funded by the Ministry of Education, Science and Technology. | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | SPRINGER | ko_KR |
dc.subject | Attenuation correction | ko_KR |
dc.subject | Brain | ko_KR |
dc.subject | Cat | ko_KR |
dc.subject | Spatial normalization | ko_KR |
dc.subject | Animal PET | ko_KR |
dc.title | Feasibility of Template-Guided Attenuation Correction in Cat Brain PET Imaging | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 김진수 | - |
dc.contributor.AlternativeAuthor | 이재성 | - |
dc.contributor.AlternativeAuthor | 박민현 | - |
dc.contributor.AlternativeAuthor | 김경민 | - |
dc.contributor.AlternativeAuthor | 오승하 | - |
dc.contributor.AlternativeAuthor | 천지영 | - |
dc.contributor.AlternativeAuthor | 송인찬 | - |
dc.contributor.AlternativeAuthor | 문대혁 | - |
dc.contributor.AlternativeAuthor | 정준기 | - |
dc.contributor.AlternativeAuthor | 이동수 | - |
dc.identifier.doi | 10.1007/s11307-009-0277-1 | - |
dc.citation.journaltitle | MOLECULAR IMAGING AND BIOLOGY | - |
dc.description.citedreference | Kim SJ, 2008, J NUCL MED, V49, P2057, DOI 10.2967/jnumed.108.053215 | - |
dc.description.citedreference | Hofmann M, 2008, J NUCL MED, V49, P1875, DOI 10.2967/jnumed.107.049353 | - |
dc.description.citedreference | Zhou VW, 2008, MOL IMAGING BIOL, V10, P315, DOI 10.1007/s11307-008-0157-0 | - |
dc.description.citedreference | Vandervoort E, 2008, J NUCL MED, V49, P1852, DOI 10.2967/jnumed.108.051193 | - |
dc.description.citedreference | Riemann B, 2008, Q J NUCL MED MOL IM, V52, P215 | - |
dc.description.citedreference | Hong SJ, 2008, IEEE T NUCL SCI, V55, P882, DOI 10.1109/TNS.2008.924082 | - |
dc.description.citedreference | Beyer T, 2008, EUR J NUCL MED MOL I, V35, P1142, DOI 10.1007/s00259-008-0734-0 | - |
dc.description.citedreference | Kim JS, 2008, MOL IMAGING BIOL, V10, P154, DOI 10.1007/s11307-008-0140-9 | - |
dc.description.citedreference | Judenhofer MS, 2008, NAT MED, V14, P459, DOI 10.1038/nm1700 | - |
dc.description.citedreference | Catana C, 2008, P NATL ACAD SCI USA, V105, P3705, DOI 10.1073/pnas.0711622105 | - |
dc.description.citedreference | van Velden FHP, 2008, PHYS MED BIOL, V53, P99, DOI 10.1088/0031-9155/53/1/007 | - |
dc.description.citedreference | Woo SK, 2008, NUCL MED BIOL, V35, P143, DOI 10.1016/j.nucmedbio.2007.10.003 | - |
dc.description.citedreference | KIM JS, 2008, NUCL MED MOL IMAGING, V42, P112 | - |
dc.description.citedreference | Kim JS, 2007, J NUCL MED, V48, P1527, DOI 10.2967/jnumed.107.040550 | - |
dc.description.citedreference | Judenhofer MS, 2007, RADIOLOGY, V244, P807, DOI 10.1148/radiol.2443061756 | - |
dc.description.citedreference | Lee JS, 2007, PHARM RES, V24, P1202, DOI 10.1007/s11095-007-9264-x | - |
dc.description.citedreference | KIM JS, 2007, J NUCL MED S, V48, P411 | - |
dc.description.citedreference | Zhang YM, 2006, MOL IMAGING BIOL, V8, P300, DOI 10.1007/s11307-006-0052-5 | - |
dc.description.citedreference | Lehnert W, 2006, PHYS MED BIOL, V51, P4003, DOI 10.1088/0031-9155/51/16/008 | - |
dc.description.citedreference | Herrero P, 2006, J NUCL MED, V47, P477 | - |
dc.description.citedreference | KIM JS, 2006, NUCL MED MOL IMAGING, V40, P40 | - |
dc.description.citedreference | Lee JS, 2005, EUR J NUCL MED MOL I, V32, P696, DOI 10.1007/s00259-004-1739-y | - |
dc.description.citedreference | Chow PL, 2005, PHYS MED BIOL, V50, P1837, DOI 10.1088/0031-9155/50/8/014 | - |
dc.description.citedreference | Montandon ML, 2005, NEUROIMAGE, V25, P278 | - |
dc.description.citedreference | Pomper MG, 2005, CURR PHARM DESIGN, V11, P3247 | - |
dc.description.citedreference | Waldherr C, 2005, J NUCL MED, V46, P114 | - |
dc.description.citedreference | Ahn SH, 2004, HEARING RES, V196, P33, DOI 10.1016/j.heares.2004.05.012 | - |
dc.description.citedreference | Green LA, 2004, J NUCL MED, V45, P1560 | - |
dc.description.citedreference | Woody C, 2004, NUCL INSTRUM METH A, V527, P166, DOI 10.1016/j.nima.2004.03.114 | - |
dc.description.citedreference | Toyama H, 2004, NUCL MED BIOL, V31, P251, DOI 10.1016/S0969-8051(03)00124-0 | - |
dc.description.citedreference | Matsumura A, 2003, NEUROIMAGE, V20, P2040, DOI 10.1016/j.neuroimage.2003.08.020 | - |
dc.description.citedreference | Knoess C, 2003, EUR J NUCL MED MOL I, V30, P737, DOI 10.1007/s00259-002-1052-6 | - |
dc.description.citedreference | Yang HH, 2003, PROSTATE, V55, P39, DOI 10.1002/pros.10208 | - |
dc.description.citedreference | Huber JS, 2002, PHYS MED BIOL, V47, P3535, DOI 10.1088/0031-9155/47/19/307 | - |
dc.description.citedreference | Burger C, 2002, EUR J NUCL MED MOL I, V29, P922, DOI 10.1007/s00259-002-0796-3 | - |
dc.description.citedreference | Weinzapfel BT, 2001, J NUCL MED, V42, P483 | - |
dc.description.citedreference | Stodilka RZ, 2000, J NUCL MED, V41, P1569 | - |
dc.description.citedreference | Watson CC, 2000, IEEE T NUCL SCI, V47, P1587, DOI 10.1109/23.873020 | - |
dc.description.citedreference | Nuyts J, 1999, IEEE T NUCL SCI, V46, P1136, DOI 10.1109/23.790847 | - |
dc.description.citedreference | Nuyts J, 1999, IEEE T MED IMAGING, V18, P393, DOI 10.1109/42.774167 | - |
dc.description.citedreference | Ashburner J, 1999, HUM BRAIN MAPP, V7, P254 | - |
dc.description.citedreference | Kinahan PE, 1998, MED PHYS, V25, P2046 | - |
dc.description.citedreference | Kalter SS, 1997, LAB ANIM SCI, V47, P461 | - |
dc.description.citedreference | Friston KJ, 1995, HUM BRAIN MAPP, V3, P165 | - |
dc.description.citedreference | SMITH RJ, 1994, IEEE T NUCL SCI, V41, P1526, DOI 10.1109/23.322943 | - |
dc.description.citedreference | SIEGEL S, 1992, IEEE T NUCL SCI, V39, P1117, DOI 10.1109/23.159770 | - |
dc.description.citedreference | XU EZ, 1991, J NUCL MED, V32, P161 | - |
dc.description.citedreference | CARSON RE, 1988, J NUCL MED, V29, P1558 | - |
dc.description.citedreference | ROGERS JG, 1987, IEEE T MED IMAGING, V6, P239 | - |
dc.description.tc | 0 | - |
- Appears in Collections:
- Files in This Item:
- There are no files associated with this item.
Item View & Download Count
Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.