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Optical Measurement of Neural Activity Using Surface Plasmon Resonance
Cited 44 time in
Web of Science
Cited 47 time in Scopus
- Authors
- Issue Date
- 2008-05
- Publisher
- Optical Society of America
- Citation
- Opt. Lett. 33, 914 (2008)
- Abstract
- We demonstrate that surface plasmon resonance (SPR) is applicable to the optical detection of neural signals.
A low-noise SPR sensor was developed as a label- and artifact-free method for the extracellular recording
of neural activity. The optical responses obtained from a rat sciatic nerve were highly correlated with
simultaneously recorded electrical responses. Additional studies with stimulation intensity and lidocaine
further confirmed that the optically measured signals originated from neural activities.
- ISSN
- 0146-9592
- Language
- English
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