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Evaluation of MRI resolution affecting trabecular bone parameters: Determination of acceptable resolution

Cited 7 time in Web of Science Cited 10 time in Scopus
Authors
Kim, Namkug; Lee, June-Goo; Song, Youngkyu; Kim, Hengjun J.; Yeom, Jin S.; Cho, Gyunggoo
Issue Date
2012-01
Publisher
JOHN WILEY & SONS INC
Citation
MAGNETIC RESONANCE IN MEDICINE Vol.67 No.1, pp. 218-225
Keywords
의약학Otsu thresholdingskeletonizationstructural analysistrabecular bone segmentation
Abstract
The objective of this study is to evaluate the effect of MR image resolution on trabecular bone parameters and to determine the acceptable resolution that can be accurately analyzed to assess structural parameters. Ten distal femoral condyle specimens of 1 x 1 x 1 cm3 were scanned with a 4.7-T Bruker BioSpec MRI scanner using a three-dimensional fast large-angle spin-echo sequence with various iso-cubic voxels sizes (65, 130, 160, 196, 230, and 260 mu m). Otsu thresholding was applied to identify voxels containing bone. Conventional bone parameters, structural bone parameters, and skeleton-based local trabecular thickness (slTB.Th) were evaluated. The BlandAltman method and correlation indicated that the conventional and structural bone parameters were preserved with an iso-cubic voxel size up to 230 mu m (r > 0.932 and r > 0.843, respectively). In addition, slTB.Th derived from the highest resolution images (65 mu m iso-cubic voxel size), correlated well (r > 0.833) with the values computed from lower resolution images, up to 230 mu m, which is twice typical human trabecular thickness range (100150 mu m). The outcome of this study suggests that the various bone parameters were well preserved up to 230 mu m images. Magn Reson Med, 2011. (C)2011 Wiley-Liss, Inc.
ISSN
0740-3194
Language
English
URI
http://hdl.handle.net/10371/81121
DOI
https://doi.org/10.1002/mrm.22984
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College of Medicine/School of Medicine (의과대학/대학원)Orthopedic Surgery (정형외과학전공)Journal Papers (저널논문_정형외과학전공)
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