굶주린 흰쥐의 혈액량

Abstract

Blood volume determinations by means of T-1824 dilution were made on two groups of rats: the first group was the normal control group consisted of 16 rats, the second group was starved for 5 days with free access to water and consisted of 18 rats. After the measurement of blood volume animals were sacrineed and the determination of lean body mass was made by means of underwater weighing. Comparisons were made between the control and the fasted group. The absolute value of plasma and blood volume was found to decrease relative to the initial body weight before the beginning of fasting in the fasted group. Plasma and blood volume. however, expressed on the basis of the final body weight or lean body mass was found to increase in the fasted group. In fasting, body weight, plasma volume and lean body mass decreased with different rate. The rate of decrease was largest in body weight and smallest in lean body mass. Therefore, plasma or blood volume relative to the final body weight showed the greater increase than the value expressed on the basis of lean body mass. In expressing plasma or blood volume in the fasted rat lean body mass was the best reference.