SHERP

Photo-Triggering of the Membrane Gates in Photo-Responsive Polymer for Drug Release

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Authors
Lee, Jae Kyoo; Lee, Hoeun; Jang, Eunje; Lee, Sin-Doo; Kim, Sung June
Issue Date
2005-09-01
Publisher
Institute of Electrical and Electronics Engineers (IEEE)
Citation
The 27th Annual International Conference of the IEEE Engineering In Medicine and Biology Society (EMBS), pp. 5069-5072, Shanghai, China, September 1-4, 2005
Abstract
The use of light stimulus for triggering drug is a promising method for accurate drug delivery. A new approach using azopolymer membrane and laser holography was investigated for developing light-triggering drug delivery system. Polymeric drug delivery system was prepared by covering azopolymer membrane on a drug agent. Holographic laser interference generated surface relief grating pattern on the azopolymer surface. The widths and depths of gates on the polymer membrane were easily modified by adjusting incident angle and irradiation time. Ar laser made the polymeric membrane permeable to the drug agent and release it in a solution. This result indicated that the azopolymer and laser holography would provide a strong foundation for the light-triggering drug delivery system.
Language
English
URI
http://hdl.handle.net/10371/8888
DOI
https://doi.org/10.1109/IEMBS.2005.1615616
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College of Engineering/Engineering Practice School (공과대학/대학원)Dept. of Electrical and Computer Engineering (전기·정보공학부)Others_전기·정보공학부
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