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Multichannel surface electrodes increase the sensitivity of diagnosis of neuropathy in diabetic patients
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Koo, Yong Seo | - |
dc.contributor.author | Jung, Ki-Young | - |
dc.contributor.author | Lee, Sang-Hoon | - |
dc.contributor.author | Cho, Charles S. | - |
dc.contributor.author | Yang, Kyung-Sook | - |
dc.contributor.author | Jang, Jae Hong | - |
dc.contributor.author | Kim, Byung-Jo | - |
dc.creator | 정기영 | - |
dc.date.accessioned | 2014-05-15T07:00:50Z | - |
dc.date.available | 2014-05-15T07:00:50Z | - |
dc.date.issued | 2013-10 | - |
dc.identifier.citation | Journal of Electromyography and Kinesiology, Vol.23 No.5, pp. 1057-1064 | - |
dc.identifier.issn | 1050-6411 | - |
dc.identifier.uri | https://hdl.handle.net/10371/91792 | - |
dc.description.abstract | This prospective study investigated the diagnostic sensitivity of a novel multichannel surface electrode for detecting electrophysiologic changes in symptomatic diabetic neuropathy. We recruited healthy subjects without neuropathic complaints and diabetic patients with distal symmetric sensory symptoms who had normal nerve conduction studies (NCS). Eight compound muscle action potentials (CMAPs) were recorded using a multichannel electrode from each subject's abductor pollicis brevis muscle by stimulating the median nerve at the wrist. Latency-and amplitude-related variables were obtained and analyzed to compare the two groups. We used the Classification and Regression Tree (CART# algorithm to determine the cut-off values for selected predictors of diabetic neuropathy. All of the variables related to CMAP latency showed statistically significant differences between the median values for the diabetic group and the healthy control group. For example, the median value of the maximum latency and standard deviation of the eight CMAP onset latencies in diabetic patients #3.82 ms and 0.15 ms, respectively# were significantly larger than those in controls #3.26 ms and p < 0.001; 0.09 ms and p < 0.001, respectively#. The CART analysis revealed that these variables were the most sensitive and specific variables for discriminating between patients with diabetic neuropathy and normal subjects. The multichannel surface electrode demonstrated both high sensitivity and specificity in detecting neurophysiologic abnormality of diabetic neuropathy, even when conventional NCS did not detect the abnormality. | en |
dc.language.iso | en | en |
dc.publisher | Elsevier | en |
dc.subject | 의약학 | en |
dc.subject | Multichannel electrode | - |
dc.subject | Diabetic neuropathies | - |
dc.subject | Early diagnosis | - |
dc.subject | Compound muscle action potentials | - |
dc.subject | Nerve conduction study | - |
dc.subject | Neural conduction | - |
dc.title | Multichannel surface electrodes increase the sensitivity of diagnosis of neuropathy in diabetic patients | en |
dc.type | Article | - |
dc.contributor.AlternativeAuthor | 구용서 | - |
dc.contributor.AlternativeAuthor | 정기영 | - |
dc.contributor.AlternativeAuthor | 이상훈 | - |
dc.contributor.AlternativeAuthor | 양경숙 | - |
dc.contributor.AlternativeAuthor | 장재홍 | - |
dc.contributor.AlternativeAuthor | 김병조 | - |
dc.identifier.doi | 10.1016/j.jelekin.2013.07.003 | - |
dc.description.srnd | OAIID:oai:osos.snu.ac.kr:snu2013-01/102/2014017262/6 | - |
dc.description.srnd | SEQ:6 | - |
dc.description.srnd | PERF_CD:SNU2013-01 | - |
dc.description.srnd | EVAL_ITEM_CD:102 | - |
dc.description.srnd | USER_ID:2014017262 | - |
dc.description.srnd | ADJUST_YN:Y | - |
dc.description.srnd | EMP_ID:A079623 | - |
dc.description.srnd | DEPT_CD:801 | - |
dc.description.srnd | CITE_RATE:1.644 | - |
dc.description.srnd | DEPT_NM:의학과 | - |
dc.description.srnd | SCOPUS_YN:Y | - |
dc.description.srnd | CONFIRM:Y | - |
dc.identifier.srnd | 2013-01/102/2014017262/6 | - |
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