거세가 흰쥐 뇌하수체 LH 세포에 미치는 면역조직화학적 연구
Immunohistochemical studies on the LH cells of pituitary glands in castrated male rats

Cited 0 time in webofscience Cited 0 time in scopus
심재도; 백상호
Issue Date
서울대학교 의과대학
Seoul J Med 1972;13(3):209-220
Pituitary glands of male rats, castrated for
varying lengths of time, between 7 and 150 days
after operation, have been studied for their histological
changes using the peroxidase-labeled antibody
Number of LH cells reacted specifically with antiHCG
and anti-RGG-peroxidase were counted from
one hundred visual fields of twenty representative
level of sections under higher magnification. There
was a tendency that the LH cells increase gradually
after castration. At the thirty days after castration,
castration cells with vacuole begin to appear and
reached up to 30% of total cell count at the 150
days after castration. On the other hand the pituitary
glands of castrated rats which were administered
testosterone propionate and testosterone cyclopentylpropionate
showed marked decrease of LH cells not
only in number but in the intensity of staining.
Proliferation of additional LH cells were found
mainly in the central zone of pituitary gland , while
the LH cells in the peripheral zone remained continuously.
The weight of pituitary glands of castrated rats
revealed a tendency of gradual increase while that
of the hormone treated castrated rats showed a
tendency of gradual decrease.
Those cellular changes are illustrated and their
possible significance is discussed.
Files in This Item:
Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Dept. of Medicine (의학과)The Seoul Journal of MedicineThe Seoul Journal of Medicine Vol. 13 No.3 (1972)
  • mendeley

Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.