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산소결핍을 동반한 급성 호흡성 산증 : Acid-Base Changes of Acute Hypoxic Respiratory acidosis in Rabbits
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- Authors
- Issue Date
- 1978-12
- Publisher
- 서울대학교 의과대학
- Citation
- Seoul J Med, Vol.19 No.4, pp. 205-210
- Abstract
- Experimental acute respiratory acidosis is mostly
induced by raising simply arterial carbon dioxide
tension , clinical respiratory acidosis , however. is
usually complicated with hypoxia. To induce hypoxic
respiratory acidosis. rabbits were introduced to air
tight chamber for few hours to 21 hours Acid·Base
data analyzed were as follows:
1. Breathing in the small chamber, environmental
air P02 decreased and PC02 increased steadily. Arterial
blood Pco, increased along with the environmental
air Pco.. although arterial blood Po, did not always
decrease with the environmental PO~. Defense against
to the hypoxia in the moderate degree of air Po,
depression was achieved by the hyperventilation
2. Up to the moderate degree of Po, depression ,
hypoxic hypercapnia were not different from hypercapnia
without hypoxia, however , the lower the Po,
the more to be combined with metabolic acidosis. two
out of seven respiratory acidosis were not combined
with metabolic acidosis at all.
3. Plasma potassium concentration were always
elevated whether it is hypoxic , or combined with
metabolic acidosis. The increment was more when
acidosis is severe and elapsed longer with acidosis
- ISSN
- 0582-6802
- Language
- Korean
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