한국아동의 단백질 영양상태에 따른 뇨중질소화합물에 관한 연구
A Study on Urinary Nitrogen Metabolites regarding Protein Nutritional Status of Children in Korea

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모수미; 채범석
Issue Date
서울대학교 의과대학
Seoul J Med 1975;16(2):102-119
Though protein malnutrition among infants, and
children is recognized as a major public health
problem in most developing countries, precise data
regarding protein intake in these age groups are
scanty. It is apparent that some universally acceptable
and practical methods for the evaluation of
protein nutritional states in order to assess the
prevalence and severity of protein malnutrition in
different parts of the world are desirable to evaluate
the effectiveness of nutrition programs for the
prevention of malnutrition.
During the last fe‘ill years, there have been
numerous reports of somewhat low excretion of
urinary nitrogen metabolites in population groups
with inadequate protein intakes. There are evidences
that the turnover of body protein is more rapid
when the protein intake is higher than when it is
lower. Various urinary urea to total nitrogen or creatinine
ratios or indexes, are tested in children from
different nutritional and socioeconomical conditions
and found that the ratios or indexes to be markedly
lower in the groups with poorer nutrition.
Determinations of anthropometric. hematologic
measurements were made as well as urinary nitrogen
excretion on 219 healthy infants and children
ranging from 1 to 11 years old. 178 urban slum preschool
children around Seoul, and 376 school children
in Jaeju Island were also studied.
Based on the evaluation of relationship between
protein intake and urinary nitrogen excretion as an
index suitable for the detection of the protein malnutrition
was described in this paper.
The results of this study were as follows: (1) In general, the means of anthropometric
measurements, height, weight, arm circumference
and skinfold thickness of urban slum preschool
children were slightly lower than the Korean
standards, and Jaeju school children were within
normal limit of Korean standards. However, healthy
infants and children ranging from I to 11 year of
age had higher levels than the Korean standards
and lower than the American standards
(2) The mean hemoglobin level of preschool
children in slum area was 11. 3 g/100ml hemoglobin
and less than 11.Og/100ml in 65 of 178 children.
School children in Jaeju had mean hemoglobin
level of 12.8g/100ml and number of children less
than 12.0g/100ml was 40 in 376 school children.
The mean hemoglobin level of healthy preschool
children was 12.9g/100ml and school children,
(3) The mean values of urea nitrogen/creatinine
nitrogen ratio of preschool children in slum area,
Jaeju school children and healthy preschool and
school children were 31.6, 25.0 , 38.1 and 40.5
(4) Relatively close relationship was observed
between urea nitrogen/creatinine nitrogen ratio and
hemoglobin level of all children, especially high in
preschool children.
(5) Relationship between hemoglobin level and
anthropometric measurements was relatively close
in all children, however, high between arm
circumference and hemoglobin. and low between
height and hemoglobin in urban preschool chil
(6) Although relationship between anthropometric
measurements and urea nitrogen/creatinine nitrogen
was hardly found , there was a slight relationship
between urea nitrogen/creatinine nitr'ogen ratio and
height, and arm circumference in preschool children
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College of Medicine/School of Medicine (의과대학/대학원)Dept. of Medicine (의학과)The Seoul Journal of MedicineThe Seoul Journal of Medicine Vol. 16 No.2 (1975)
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