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Showing results 1 to 35 of 35

Issue Date	Title / Author(s) / Citation	File
2012-07	Fyn Inhibition by Cycloalkane-Fused 1,2-Dithiole-3-thiones Enhances Antioxidant Capacity and Protects Mitochondria from Oxidative Injury Koo, Ja Hyun; Lee, Woo Hyung; Lee, Chan Gyu; Kim, Sang Geon Molecular Pharmacology, Vol.82 No.1, pp.27-36	DOI
2013-10	miR-125b transcriptionally increased by Nrf2 inhibits AhR repressor, which protects kidney from cisplatin-induced injury Joo, M. S.; Lee, C. G.; Koo, J. H.; Kim, S. G. Cell Death and Disease, Vol.4 No.10, p. e899	DOI
2014-05	microRNA-148a dysregulation discriminates poor prognosis of hepatocellular carcinoma in association with USP4 overexpression Heo, Mi Jeong; Kim, Young Mi; Koo, Ja Hyun; Yang, Yoon Mee; An, Jihyun; Lee, Sook-Kyung; Lee, Seung Jin; Kim, Kang Mo; Park, Joong-Won; Kim, Sang Geon Oncotarget, Vol.5 No.9, pp.2792-2806	DOI
2014-07	Gα12 gep oncogene inhibits FOXO1 in hepatocellular carcinoma as a consequence of miR-135b and miR-194 dysregulation Jung, Hye Sun; Seo, Yu-Ri; Yang, Yoon Mee; Koo, Ja Hyun; An, Jihyun; Lee, Seung Jin; Kim, Kang Mo; Kim, Sang Geon Cellular Signalling, Vol.26 No.7, pp.1456-1465	DOI
2015-08	Gα12 overexpressed in hepatocellular carcinoma reduces microRNA-122 expression via HNF4α inactivation, which causes c-Met induction Yang, Yoon Mee; Lee, Chan Gyu; Koo, Ja Hyun; Kim, Tae Hyun; Lee, Jung Min; An, Jihyun; Kim, Kang Mo; Kim, Sang Geon Oncotarget, Vol.6 No.22, pp.19055-19069	DOI
2015-12	Phytochemical regulation of Fyn and AMPK signaling circuitry Lee, Chan Gyu; Koo, Ja Hyun; Kim, Sang Geon Archives of Pharmacal Research, Vol.38 No.12, pp.2093-2105	DOI
2016-01	Endoplasmic reticulum stress in hepatic stellate cells promotes liver fibrosis via PERK-mediated degradation of HNRNPA1 and up-regulation of SMAD2 Koo, Ja Hyun; Lee, Hyo Ju; Kim, Won; Kim, Sang Geon Gastroenterology, Vol.150 No.1, pp.181-193.e8	DOI
2016-07	AMPK facilitates nuclear accumulation of Nrf2 by phosphorylating at serine 550 Joo, Min Sung; Kim, Won Dong; Lee, Ki Young; Kim, Ji Hyun; Koo, Ja Hyun; Kim, Sang Geon Molecular and Cellular Biology, Vol.36 No.14, pp.1931-1942	DOI
2016-08	PHLDA3 overexpression in hepatocytes by endoplasmic reticulum stress via IRE1-Xbp1s pathway expedites liver injury Han, Chang Yeob; Lim, Sang Woo; Koo, Ja Hyun; Kim, Won; Kim, Sang Geon Gut, Vol.65 No.8, pp.1377-1388	DOI
2016-08	Farnesoid X receptor as a regulator of fuel consumption and mitochondrial function Han, Chang Yeob; Kim, Tae Hyun; Koo, Ja Hyun; Kim, Sang Geon Archives of Pharmacal Research, Vol.39 No.8, pp.1062-1074	DOI
2016-12	Hepcidin inhibits Smad3 phosphorylation in hepatic stellate cells by impeding ferroportin-mediated regulation of Akt Han, Chang Yeob; Koo, Ja Hyun; Kim, Sung Hoon; Gardenghi, Sara; Rivella, Stefano; Strnad, Pavel; Hwang, Se Jin; Kim, Sang Geon Nature Communications, Vol.7, p. 13817	DOI
2017-05	Oligopeptide Competition Assay for Phosphorylation Site Determination Joo, Min Sung; Koo, Ja Hyun; Shin, Sol-Bi; Yim, Hyungshin; Kim, Sang Geon Journal of Visualized Experiments, Vol.2017 No.123, p. e55708	DOI
2017-10	Gα13 ablation reprograms myofibers to oxidative phenotype and enhances whole-body metabolism Koo, Ja Hyun; Kim, Tae Hyun; Park, Shi-Young; Joo, Min Sung; Han, Chang Yeob; Choi, Cheol Soo; Kim, Sang Geon Journal of Clinical Investigation, Vol.127 No.10, pp.3845-3860	DOI
2018-02	Gα12 regulates osteoclastogenesis by modulating NFATc1 expression Song, Min-Kyoung; Park, Cheolkyu; Lee, Yong Deok; Kim, Haemin; Kim, Min Kyung; Kwon, Jun-Oh; Koo, Ja Hyun; Joo, Min Sung; Kim, Sang Geon; Kim, Hong-Hee Journal of Cellular and Molecular Medicine, Vol.22 No.2, pp.849-860	DOI
2018-03	Gα12 overexpression induced by miR16 dysregulation contributes to liver fibrosis by promoting autophagy in hepatic stellate cells Kim, Kyu Min; Han, Chang Yeob; Kim, Ji Young; Cho, Sam Seok; Kim, Yun Seok; Koo, Ja Hyun; Lee, Jung Min; Lim, Sung Chul; Kang, Keon Wook; Kim, Jae-Sung; Hwang, Se Jin; Ki, Sung Hwan; Kim, Sang Geon Journal of Hepatology, Vol.68 No.3, pp.493-504	DOI
2018-08	Interplay between YAP/TAZ and Metabolism Koo, Ja Hyun; Guan, Kun-Liang Cell Metabolism, Vol.28 No.2, pp.196-206	DOI
2018-12	G alpha(12) ablation exacerbates liver steatosis and obesity by suppressing USP22/SIRT1-regulated mitochondrial respiration Kim, Tae Hyun; Yang, Yoon Mee; Han, Chang Yeob; Koo, Ja Hyun; Oh, Hyunhee; Kim, Su Sung; You, Byoung Hoon; Choi, Young Hee; Park, Tae-Sik; Lee, Chang Ho; Kurose, Hitoshi; Noureddin, Mazen; Seki, Ekihiro; Wan, Yu-Jui Yvonne; Choi, Cheol Soo; Kim, Sang Geon Journal of Clinical Investigation, Vol.128 No.12, pp.5587-5602	DOI
2019-02	LRH1-driven transcription factor circuitry for hepatocyte identity: Super-enhancer cistromic analysis Joo, Min Sung; Koo, Ja Hyun; Kim, Tae Hyun; Kim, Yun Seok; Kim, Sang Geon EBioMedicine, Vol.40, pp.488-503	DOI
2019-04	Cell type-dependent function of LATS1/2 in cancer cell growth Pan, Wei-Wei; Toshiro, Moroishi; Koo, Ja Hyun; Guan, Kun-Liang Oncogene, Vol.38 No.14, pp.2595-2610	DOI
2019-07	Nrf2-lncRNA controls cell fate by modulating p53-dependent Nrf2 activation as an miRNA sponge for Plk2 and p21(cip1) Joo, Min Sung; Shin, Sol-Bi; Kim, Eun Jung; Koo, Hyun Ja; Yim, Hyungshin; Kim, Sang Geon FASEB Journal, Vol.33 No.7, pp.7953-7969	DOI
2019-10	Overproduction of inter-α-trypsin inhibitor heavy chain 1 after loss of Gα13 in liver exacerbates systemic insulin resistance in mice Kim, Tae Hyun; Koo, Ja Hyun; Heo, Mi Jeong; Han, Chang Yeob; Kim, Yong-In; Park, Shi-Young; Cho, Il Je; Lee, Chang Ho; Choi, Cheol Soo; Lee, Jung Weon; Kim, Won; Cho, Je-Yoel; Kim, Sang Geon Science Translational Medicine, Vol.11 No.513, p. eaan4735	DOI
2019-10	Liver X Receptor α-Induced Cannabinoid Receptor 2 Inhibits Ubiquitin-Specific Peptidase 4 Through miR-27b, Protecting Hepatocytes From TGF-β Wu, Hong Min; Kim, Tae Hyun; Koo, Ja Hyun; Joo, Min Sung; Kim, Sang Geon Hepatology Communications, Vol.3 No.10, pp.1373-1387	DOI
2020-01	Induction of AP-1 by YAP/TAZ contributes to cell proliferation and organ growth Koo, Ja Hyun; Plouffe, Steven W.; Meng, Zhipeng; Lee, Da-Hye; Yang, Di; Lim, Dae-Sik; Wang, Cun-Yu; Guan, Kun-Liang Genes and Development, Vol.34 No.1-2, pp.72-86	DOI
2021-02	Signaling Nodes Associated with Endoplasmic Reticulum Stress during NAFLD Progression Koo, Ja Hyun; Han, Chang Yeob Biomolecules, Vol.11 No.2, pp.242-15	DOI
2021-12	Ablation of USP21 in skeletal muscle promotes oxidative fibre phenotype, inhibiting obesity and type 2 diabetes Kim, Ayoung; Koo, Ja Hyun; Jin, Xing; Kim, Wondong; Park, Shi-Young; Park, Sunghyouk; Rhee, Eugene P.; Choi, Cheol Soo; Kim, Sang Geon Journal of Cachexia, Sarcopenia and Muscle, Vol.12 No.6, pp.1669-1689	DOI
2022-03	NRF2-mediated SIRT3 induction protects hepatocytes from ER stress-induced liver injury Kim, Ayoung; Koo, Ja Hyun; Lee, Jung Min; Joo, Min Sung; Kim, Tae Hyun; Kim, Hyunsung; Jun, Dae Won; Kim, Sang Geon FASEB Journal, Vol.36 No.3, p. e22170	DOI
2022-11	Nuclear factor (erythroid-derived 2)-like 2 counter-regulates thymosin beta-4 expression and primary cilium formation for HeLa cervical cancer cell survival Lee, Jae-Wook; Thuy, Pham Xuan; Koo, Ja Hyun; Moon, Eun-Yi Scientific Reports, Vol.12 No.1, p. 20170	DOI
2023-01	Identification of Small GTPases That Phosphorylate IRF3 through TBK1 Activation Using an Active Mutant Library Screen Yu, Jae-Hyun; Moon, Eun-Yi; Kim, Jiyoon; Koo, Ja Hyun Biomolecules & Therapeutics, Vol.31 No.1, pp.48-58	DOI
2023-02	ERdj5 protects goblet cells from endoplasmic reticulum stress-mediated apoptosis under inflammatory conditions Jeong, Hyunjin; Hong, Eun-Hye; Ahn, Jae-Hee; Cho, Jaewon; Jeong, Jae-Hyeon; Kim, Chae-Won; Yoon, Byung-Il; Koo, Ja Hyun; Park, Yun-Yong; Yang, Yoon Mee; Iwawaki, Takao; Vallance, Bruce A.; Chang, Sun-Young; Ko, Hyun-Jeong Experimental and Molecular Medicine, Vol.55 No.2, pp.401-412	DOI
2023-11	Identification of the primary ciliary proteins IFT38 and IFT144 to enhance serum-mediated YAP activation and cell proliferation Yu, Jae-Hyun; Kim, Jeong Heon; Soung, Nak-Kyun; Moon, Eun-Yi; Koo, Ja Hyun Biochemical and Biophysical Research Communications, Vol.681, pp.186-193	DOI
2024-01	Mitochondrial stress activates YAP/TAZ through RhoA oxidation to promote liver injury Kwon, Ari'; Lee, Na Young; Yu, Jae-Hyun; Choi, Myeung Gi; Park, Jeongwoo; Koo, Ja Hyun Cell Death and Disease, Vol.15 No.1, p. 51	DOI
2024-01	Hepatocyte GPCR signaling regulates IRF3 to control hepatic stellate cell transdifferentiation Yu, Jae-Hyun; Choi, Myeung Gi; Lee, Na Young; Kwon, Ari; Lee, Euijin; Koo, Ja Hyun Cell Communication and Signaling, Vol.22 No.1, p. 48	DOI
2024-05	Endoplasmic Reticulum Stress Activates Hepatic Macrophages through PERK-hnRNPA1 Signaling Kwon, Ari; Kim, Yun Seok; Kim, Jiyoon; Koo, Ja Hyun Biomolecules and Therapeutics, Vol.32 No.3, pp.341-348	DOI
2024-06	Interplay between YAP/TAZ and metabolic dysfunction-associated steatotic liver disease progression Lee, Na Young; Choi, Myeung Gi; Lee, Eui Jin; Koo, Ja Hyun Archives of Pharmacal Research, Vol.47 No.6, pp.558-570	DOI
2024-12	Longitudinal evaluation of liver stiffness reveals hepatic cholesterol as the determinant of fibrosis progression in mice Lee, Na Young; Koo, Ja Hyun Life Sciences, Vol.358, p. 123201	DOI