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Stepwise tapering of remifentanil at the end of surgery decreased postoperative pain and the need of rescue analgesics after thyroidectomy
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Han, Sun Sook | - |
dc.contributor.author | Do, Sang Hwan | - |
dc.contributor.author | Kim, Tae Hee | - |
dc.contributor.author | Choi, Won Joon | - |
dc.contributor.author | Yun, Ji Sup | - |
dc.contributor.author | Ryu, Jung Hee | - |
dc.date.accessioned | 2017-02-06T01:55:37Z | - |
dc.date.available | 2017-02-06T01:55:37Z | - |
dc.date.issued | 2015-04-08 | - |
dc.identifier.citation | BMC Anesthesiology, 15(1):46 | ko_KR |
dc.identifier.uri | https://hdl.handle.net/10371/100429 | - |
dc.description | This is an Open Access article distributed under the terms of the Creative
Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. | ko_KR |
dc.description.abstract | Abstract
Background This study was designed to investigate whether stepwise tapering of remifentanil at the end of surgery could decrease postoperative pain scores and requirements of rescue analgesics after remifentanil-desflurane anesthesia in patients with thyroidectomy. Methods Sixty two patients undergoing thyroidectomy under general anesthesia were randomly allocated into two groups. All patients were anesthetised with desflurane and high-dose remifentanil. Remifentnail was infused at the rate of 0.3μg/kg/min until the end of surgery in patients of the control group (group A) whereas remifentanil was tapered gradually from 0.3 to 0.1μg/kg/min until the end of surgery for at least 30minutes in patients with group B. Pain scores (0–100 numerical rating scale, NRS), rescue analgesic requirements and adverse events were assessed at 30min, 2h, 6h, 12h, and 24h after operation. Results There was a significant decrease in pain scores at 30min (20 [0–80] vs. 50 [0–100], P = 0.002) and 2h (30 [10–60] vs. 40 [20–80], P = 0.018) after surgery in group B compared with group A. In addition, rescue analgesics are less required in group B than in group A postoperatively (2 [1-3] vs. 3 [2,3], P = 0.039). There were no significant differences in adverse events between the two groups. Conclusions Tapering of remifentanil at the end of surgery decreased postoperative pain scores immediately after thyroidectomy with desflurane and high-dose remifentanil anesthesia. Trial registration Clinical Research information Service (CRiS, registration number KCT0000589 ). | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | BioMed Central | ko_KR |
dc.subject | Anesthetic volatile-desflurane | ko_KR |
dc.subject | Analgesics opioid- remifentanil | ko_KR |
dc.subject | Complications-hyperalgesia | ko_KR |
dc.title | Stepwise tapering of remifentanil at the end of surgery decreased postoperative pain and the need of rescue analgesics after thyroidectomy | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 한선숙 | - |
dc.contributor.AlternativeAuthor | 도상환 | - |
dc.contributor.AlternativeAuthor | 김태희 | - |
dc.contributor.AlternativeAuthor | 최원준 | - |
dc.contributor.AlternativeAuthor | 윤지섭 | - |
dc.contributor.AlternativeAuthor | 류정희 | - |
dc.identifier.doi | 10.1186/s12871-015-0026-8 | - |
dc.language.rfc3066 | en | - |
dc.rights.holder | Han et al.; licensee BioMed Central. | - |
dc.date.updated | 2017-01-06T09:58:45Z | - |
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