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Determination of optimal timing window for pulmonary artery MDCT angiography

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dc.contributor.authorLee, Chang Hyun-
dc.contributor.authorGoo, Jin Mo-
dc.contributor.authorLee, Hyun Ju-
dc.contributor.authorKim, Kwang Gi-
dc.contributor.authorIm, Jung-Gi-
dc.contributor.authorBae, Kyongtae T.-
dc.date.accessioned2009-10-17T01:48:15Z-
dc.date.available2009-10-17T01:48:15Z-
dc.date.issued2007-
dc.identifier.citationAJR 2007; 188:313-317en
dc.identifier.issn1546-3141 (Electronic)-
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17242236-
dc.identifier.urihttps://hdl.handle.net/10371/10481-
dc.description.abstractOBJECTIVE: The purpose of our study was to determine the optimal timing window for pulmonary artery MDCT angiography. SUBJECTS AND METHODS: We prospectively studied 150 patients. Routine chest CT scans were acquired using 1.3 mL/kg of contrast medium (370 mg I/mL) that was injected at a fixed injection duration of 30 seconds, followed by a 10-second saline chase. To measure early contrast enhancement, sequential monitoring scans were obtained every 2 seconds over a fixed level of the main pulmonary artery 5 seconds after the start of the injection. Then helical diagnostic scans were obtained at three different predetermined scanning delays (group A, 25 seconds; group B, 35 seconds; and group C, 45 seconds after the start of the injection). Time-enhancement curves; time to reach 100 H, 200 H, and peak enhancement; and enhancement duration greater than 200 H of the pulmonary artery were measured from the monitoring scan. Contrast enhancements of the pulmonary artery and descending aorta and vascular artifacts were assessed from the diagnostic scan. RESULTS: Times to reach 100 H and 200 H at the pulmonary artery were mean 11 +/- 2.5 (SD) seconds and 16 +/- 3.0 seconds, respectively. Pulmonary artery enhancement duration of greater than 200 H was 25 +/- 2.7 seconds (only obtained in group C). Mean time to peak enhancement (335 +/- 62 H) at the pulmonary artery was 37 seconds. Mean enhancement measured on the diagnostic scan was 294 +/- 43 H, group A; 208 +/- 48 H, group B; and 157 +/- 15 H, group C for the pulmonary artery, and 240 +/- 42 H, group A; 277 +/- 49 H, group B; and 172 +/- 29 H, group C for the aorta (p < 0.01). Artifacts were noted in the superior vena cava (group A, 96.7%; group B, 18.3%; and group C, 0%) and in the subclavian vein (group A, 93.5%; group B, 38.7%; and group C, 0%), (p < 0.05). CONCLUSION: With our study protocol of a 30-second injection and 10-second saline flush, the optimal temporal window to achieve pulmonary artery enhancement greater than 200 H was from 16 seconds to 41 seconds after the start of the injection.en
dc.language.isoenen
dc.publisherAmerican Roentgen Ray Societyen
dc.subjectAdulten
dc.subjectAgeden
dc.subjectAged, 80 and overen
dc.subjectAngiography/*methodsen
dc.subjectContrast Media/administration & dosageen
dc.subjectFemaleen
dc.subjectHumansen
dc.subjectIohexol/administration & dosage/*analogs & derivatives/diagnostic useen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectPulmonary Artery/*radiographyen
dc.subjectPulmonary Embolism/*radiographyen
dc.subjectRadiographic Image Enhancement/*methodsen
dc.subjectReproducibility of Resultsen
dc.subjectSensitivity and Specificityen
dc.subjectTime Factorsen
dc.subjectTomography, X-Ray Computed/*methodsen
dc.titleDetermination of optimal timing window for pulmonary artery MDCT angiographyen
dc.typeArticleen
dc.contributor.AlternativeAuthor이창현-
dc.contributor.AlternativeAuthor구진모-
dc.contributor.AlternativeAuthor이현주-
dc.contributor.AlternativeAuthor김광기-
dc.contributor.AlternativeAuthor임정기-
dc.contributor.AlternativeAuthor배경태-
dc.identifier.doi10.2214/AJR.06.0078-
Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Dept. of Radiation Applied Life Science (대학원 협동과정 방사선응용생명과학전공)Journal Papers (저널논문_방사선응용생명과학전공)
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