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Determination of optimal timing window for pulmonary artery MDCT angiography
DC Field | Value | Language |
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dc.contributor.author | Lee, Chang Hyun | - |
dc.contributor.author | Goo, Jin Mo | - |
dc.contributor.author | Lee, Hyun Ju | - |
dc.contributor.author | Kim, Kwang Gi | - |
dc.contributor.author | Im, Jung-Gi | - |
dc.contributor.author | Bae, Kyongtae T. | - |
dc.date.accessioned | 2009-10-17T01:48:15Z | - |
dc.date.available | 2009-10-17T01:48:15Z | - |
dc.date.issued | 2007 | - |
dc.identifier.citation | AJR 2007; 188:313-317 | en |
dc.identifier.issn | 1546-3141 (Electronic) | - |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17242236 | - |
dc.identifier.uri | https://hdl.handle.net/10371/10481 | - |
dc.description.abstract | OBJECTIVE: The purpose of our study was to determine the optimal timing window for pulmonary artery MDCT angiography. SUBJECTS AND METHODS: We prospectively studied 150 patients. Routine chest CT scans were acquired using 1.3 mL/kg of contrast medium (370 mg I/mL) that was injected at a fixed injection duration of 30 seconds, followed by a 10-second saline chase. To measure early contrast enhancement, sequential monitoring scans were obtained every 2 seconds over a fixed level of the main pulmonary artery 5 seconds after the start of the injection. Then helical diagnostic scans were obtained at three different predetermined scanning delays (group A, 25 seconds; group B, 35 seconds; and group C, 45 seconds after the start of the injection). Time-enhancement curves; time to reach 100 H, 200 H, and peak enhancement; and enhancement duration greater than 200 H of the pulmonary artery were measured from the monitoring scan. Contrast enhancements of the pulmonary artery and descending aorta and vascular artifacts were assessed from the diagnostic scan. RESULTS: Times to reach 100 H and 200 H at the pulmonary artery were mean 11 +/- 2.5 (SD) seconds and 16 +/- 3.0 seconds, respectively. Pulmonary artery enhancement duration of greater than 200 H was 25 +/- 2.7 seconds (only obtained in group C). Mean time to peak enhancement (335 +/- 62 H) at the pulmonary artery was 37 seconds. Mean enhancement measured on the diagnostic scan was 294 +/- 43 H, group A; 208 +/- 48 H, group B; and 157 +/- 15 H, group C for the pulmonary artery, and 240 +/- 42 H, group A; 277 +/- 49 H, group B; and 172 +/- 29 H, group C for the aorta (p < 0.01). Artifacts were noted in the superior vena cava (group A, 96.7%; group B, 18.3%; and group C, 0%) and in the subclavian vein (group A, 93.5%; group B, 38.7%; and group C, 0%), (p < 0.05). CONCLUSION: With our study protocol of a 30-second injection and 10-second saline flush, the optimal temporal window to achieve pulmonary artery enhancement greater than 200 H was from 16 seconds to 41 seconds after the start of the injection. | en |
dc.language.iso | en | en |
dc.publisher | American Roentgen Ray Society | en |
dc.subject | Adult | en |
dc.subject | Aged | en |
dc.subject | Aged, 80 and over | en |
dc.subject | Angiography/*methods | en |
dc.subject | Contrast Media/administration & dosage | en |
dc.subject | Female | en |
dc.subject | Humans | en |
dc.subject | Iohexol/administration & dosage/*analogs & derivatives/diagnostic use | en |
dc.subject | Male | en |
dc.subject | Middle Aged | en |
dc.subject | Pulmonary Artery/*radiography | en |
dc.subject | Pulmonary Embolism/*radiography | en |
dc.subject | Radiographic Image Enhancement/*methods | en |
dc.subject | Reproducibility of Results | en |
dc.subject | Sensitivity and Specificity | en |
dc.subject | Time Factors | en |
dc.subject | Tomography, X-Ray Computed/*methods | en |
dc.title | Determination of optimal timing window for pulmonary artery MDCT angiography | en |
dc.type | Article | en |
dc.contributor.AlternativeAuthor | 이창현 | - |
dc.contributor.AlternativeAuthor | 구진모 | - |
dc.contributor.AlternativeAuthor | 이현주 | - |
dc.contributor.AlternativeAuthor | 김광기 | - |
dc.contributor.AlternativeAuthor | 임정기 | - |
dc.contributor.AlternativeAuthor | 배경태 | - |
dc.identifier.doi | 10.2214/AJR.06.0078 | - |
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