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A glycosidic isoflavonoid from Viola hondoensis W. BECKER et H. BOISSIEU (Violaceae), and its effect on the expression of matrix metalloproteinase-1 caused by ultraviolet irradiation in cultured human skin fibroblasts
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- Authors
- Issue Date
- 2005
- Publisher
- Pharmaceutical Society of Japan
- Citation
- Biol. Pharm. Bull., 28,1123-1125
- Keywords
- Viola hondoensis ; tectoridin-4′-O-β-D-glucoside ; matrix metalloproteinase ; human skin fibroblasts
- Abstract
- Isolation of the ethyl acetate soluble fraction from aerial parts of Viola hondoensis W. BECKER et H. BOISSIEU yielded one major isoflavonoid glycoside, tectoridin-4'-O-beta-D-glucoside. The structure of the compound was certainly determined by chemical analyses, as well as 1D- and 2D-NMR spectroscopy. The compound exhibited potent inhibitory activity against the expression of matrix metalloproteinase-1 caused by UV-irradiation in cultured human skin fibroblasts.
- ISSN
- 0918-6158 (Print)
- Language
- English
- URI
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15930761
https://hdl.handle.net/10371/10893
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